Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,938 questions · 1,994 findings · 246 reviews · Headline outcomes only

No studies found 490 · 24.6%GRADE not reported 71 · 3.6%Very low 669 · 33.6%Low 446 · 22.4%Moderate 264 · 13.2%High 54 · 2.7%

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Mortality within the longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

It is very uncertain whether pulmonary artery perfusion with blood changes all‐cause mortality within longest compared with no perfusion during cardiopulmonary bypass (very low certainty).

1 finding from 1 review

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Number of participants with pulmonary events within longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Participants with ≥ 1SAE within longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

It is very uncertain whether pulmonary artery perfusion with blood changes participants with ≥ 1SAE within longest compared with no perfusion during cardiopulmonary bypass (very low certainty).

1 finding from 1 review

Enteral vs parenteral nutrition

All‐cause mortality · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

Enteral showed no clear difference in mortality compared with parenteral nutrition (low certainty).

1 finding from 1 review

Enteral vs enteral and parenteral nutrition

Ventilator‐free days up to day 28 · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

The review found no eligible studies for this question.

1 finding from 1 review

Enteral vs enteral and parenteral nutrition

Adverse events: aspiration (as reported by study authors at end of study · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

The review found no eligible studies for this question.

1 finding from 1 review

Enteral vs enteral and parenteral nutrition

Adverse events: sepsis (as reported by study authors at end of study · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

The review found no eligible studies for this question.

1 finding from 1 review

Enteral vs enteral and parenteral nutrition

Adverse events ‐ pneumonia · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

It is very uncertain whether enteral changes adverse events: pneumonia (as reported by study authors at end of… compared with enteral and parenteral nutrition (very low certainty).

1 finding from 1 review

Enteral vs enteral and parenteral nutrition

Adverse events: Vomiting · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

The review found no eligible studies for this question.

1 finding from 1 review

Enteral vs parenteral nutrition

Number of ICU‐free days up to day 28 · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

The review found no eligible studies for this question.

1 finding from 1 review

Enteral vs parenteral nutrition

Adverse events: aspiration (as reported by study authors at end of study · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

It is very uncertain whether enteral changes adverse events: aspiration (as reported by study authors at end of… compared with parenteral nutrition (very low certainty).

1 finding from 1 review

Enteral vs parenteral nutrition

Adverse events: sepsis (as reported by study authors at end of study · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

Enteral may leads to lower adverse events: sepsis (as reported by study authors at end of study compared with parenteral nutrition (low certainty).

1 finding from 1 review

Enteral vs parenteral nutrition

Adverse events ‐ pneumonia · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

Enteral showed no clear difference in adverse events: pneumonia (as reported by study authors at end of… compared with parenteral nutrition (low certainty).

1 finding from 1 review

Enteral vs parenteral nutrition

Adverse events: Vomiting · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

It is very uncertain whether enteral changes adverse events: vomiting (as reported by study authors at end of study compared with parenteral nutrition (very low certainty).

1 finding from 1 review

Enteral vs enteral and parenteral nutrition

All‐cause mortality · critically ill adults admitted to the ICU for trauma, emergency, or post‐surgical care; population excludes participants with acute…

Enteral showed no clear difference in mortality compared with enteral and parenteral nutrition (low certainty).

1 finding from 1 review