Intervention not reported
Pain Intensity: short‐term · Patients with subacute/chronic mechanical neck pain
1 finding from 1 review
- no estimate extracted1 study · 108 participantsLow
Findings
What do systematic reviews say?
1,733 questions · 1,794 findings · 326 reviews · Headline outcomes only
No studies found 243 · 13.5%GRADE not reported 96 · 5.4%Very low 597 · 33.3%Low 506 · 28.2%Moderate 303 · 16.9%High 49 · 2.7%
BENZODIAZEPINES AS SOLE TREATMENT vs placebo
No clinically important response to treatment ‐ short term · patients with schizophrenia
It is very uncertain whether BENZODIAZEPINES AS SOLE TREATMENT changes no clinically important response to treatment ‐ short term compared with PLACEBO (very low certainty).
1 finding from 1 review
- RR 0.67 [0.44, 1.02]6 studies · 382 participantsVery low
Benzodiazepines vs antipsychotics
Desired sedation ‐ ultra short term ‐ asleep at 12 hours · patients with schizophrenia
BENZODIAZEPINES showed no clear difference in desired sedation ‐ ultra short term ‐ asleep at 12 hours compared with ANTIPSYCHOTICS (low certainty).
1 finding from 1 review
- RR 0.75 [0.44, 1.3]1 study · 66 participantsLow
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS vs placebo/no adjunctive treatment + antipsychotics
No clinically important response to treatment ‐ ultra short term (at 12 hours) · patients with schizophrenia
It is very uncertain whether ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS changes no clinically important response to treatment ‐ ultra short term (at… compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (very low certainty).
2 findings from 1 review
- RR 0.07 [0, 1.13]1 study · 45 participantsVery low
- RR 0.85 [0.51, 1.41]1 study · 67 participantsLow
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS vs placebo/no adjunctive treatment + antipsychotics
No clinically important response to treatment ‐ short term · patients with schizophrenia
It is very uncertain whether ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS changes no clinically important response to treatment ‐ short term (3 weeks… compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (very low certainty).
1 finding from 1 review
- RR 0.87 [0.49, 1.54]6 studies · 511 participantsVery low
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS vs placebo/no adjunctive treatment + antipsychotics
Adverse effects (drop‐outs due to adverse effects4) · patients with schizophrenia
It is very uncertain whether ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS changes leaving the study early due to adverse effects (overall tolerability… compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (very low certainty).
1 finding from 1 review
- RR 3.24 [0.68, 15.45]6 studies · 415 participantsVery low
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS vs placebo/no adjunctive treatment + antipsychotics
Desired sedation ‐ ultra short term ‐ tranquillised at 60 minutes · patients with schizophrenia
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS may leads to higher desired sedation ‐ ultra short term ‐ tranquillised at 60 minutes compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (low certainty).
1 finding from 1 review
- RR 1.39 [1.06, 1.83]1 study · 45 participantsLow
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS vs placebo/no adjunctive treatment + antipsychotics
Desired sedation ‐ ultra short term ‐ asleep at 12 hours · patients with schizophrenia
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS showed no clear difference in desired sedation ‐ ultra short term ‐ asleep at 12 hours compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (low certainty).
1 finding from 1 review
- RR 0.85 [0.51, 1.41]1 study · 67 participantsLow
Benzodiazepines vs antipsychotics
No clinically important response to treatment ‐ ultra short term (at 12 hours) · patients with schizophrenia
It is very uncertain whether BENZODIAZEPINES changes no clinically important response to treatment ‐ ultra short term (at… compared with ANTIPSYCHOTICS (very low certainty).
2 findings from 1 review
- RR 0.61 [0.2, 1.86]1 study · 44 participantsVery low
- RR 0.75 [0.44, 1.3]1 study · 66 participantsLow
Benzodiazepines vs antipsychotics
No clinically important response to treatment ‐ short term · patients with schizophrenia
It is very uncertain whether BENZODIAZEPINES changes no clinically important response to treatment ‐ short term compared with ANTIPSYCHOTICS (very low certainty).
1 finding from 1 review
- RR 1.48 [0.64, 3.46]2 studies · 112 participantsVery low
Technology‐mediated psychoeducation + standard care intervention vs usual care
Global state: not improved ‐ short‐term GAF · schizophrenia
Technology‐mediated psychoeducation + standard care intervention showed no clear difference in global state: not improved ‐ short‐term GAF compared with standard care intervention (low certainty).
1 finding from 1 review
- Information and communication technology in patient education and support for people with schizophrenia 2012 · Cochrane Headline outcomes onlyRR 1.15 [0.86, 1.54]1 study · 56 participantsLow
Technology‐mediated psychoeducation vs usual care
Clinical response: no clinically significant response in mental state · schizophrenia
Technology‐mediated psychoeducation showed no clear difference in mental state: not improved ‐ short‐term BPRS compared with standard care intervention (low certainty).
1 finding from 1 review
- Information and communication technology in patient education and support for people with schizophrenia 2012 · Cochrane Headline outcomes onlyRR 0.75 [0.56, 1]1 study · 84 participantsLow
Technology‐mediated psychoeducation vs usual care
Global state: not improved ‐ short‐term GAF · schizophrenia
Technology‐mediated psychoeducation showed no clear difference in global state: not improved ‐ short‐term GAF compared with standard care intervention (low certainty).
1 finding from 1 review
- Information and communication technology in patient education and support for people with schizophrenia 2012 · Cochrane Headline outcomes onlyRR 1.08 [0.82, 1.42]1 study · 84 participantsLow
Technology‐mediated psychoeducation + standard care intervention vs usual care
Clinical response: no clinically significant response in mental state · schizophrenia
Technology‐mediated psychoeducation + standard care intervention showed no clear difference in mental state: not improved ‐ short‐term BPRS compared with standard care intervention (low certainty).
1 finding from 1 review
- Information and communication technology in patient education and support for people with schizophrenia 2012 · Cochrane Headline outcomes onlyRR 0.86 [0.63, 1.19]1 study · 56 participantsLow
Intervention not reported
Leaving the study early ‐ Adverse event: Short‐term · schizophrenia
The intervention showed no clear difference in leaving the study early ‐ Adverse event: Short‐term; GRADE not reported.
1 finding from 1 review
- RR 1.91 [0.8, 4.61]6 studies · 428 participantsGRADE not reported
Intervention not reported
Cognitive function: 3. Short‐term ‐ Average end point score on various subscales of WAIS III (high = favourable) ‐ Digit symbol score · schizophrenia
1 finding from 1 review
- no estimate extracted1 study · 73 participantsGRADE not reported
Intervention not reported
Cognitive function: 4. Short‐term ‐ Average end point score on various subscales of HVLT (high = favourable) ‐ Recognition · schizophrenia
1 finding from 1 review
- no estimate extracted2 studies · 48 participantsGRADE not reported
Intervention not reported
Adverse event: 11a. Short‐term ‐ Average end point score on EPSEs scale (low = favourable) ‐ AIMS · schizophrenia
1 finding from 1 review
- no estimate extracted1 study · 35 participantsGRADE not reported
Intervention not reported
Quality of life ‐ Physical health domain SF‐36 Short form · patients with type 1 diabetes mellitus
1 finding from 1 review
- Continuous glucose monitoring systems for type 1 diabetes mellitus 2012 · Cochrane Headline outcomes onlyno estimate extracted1 study · 75 participantsVery low
Intervention not reported
Quality of life ‐ Mental health domain SF‐36 Short form · patients with type 1 diabetes mellitus
1 finding from 1 review
- Continuous glucose monitoring systems for type 1 diabetes mellitus 2012 · Cochrane Headline outcomes onlyno estimate extracted1 study · 75 participantsVery low