ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS vs placebo/no adjunctive treatment + antipsychotics: No clinically important response to treatment ‐ ultra short term (at 12 hours)
It is very uncertain whether ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS changes no clinically important response to treatment ‐ ultra short term (at… compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS vs PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS No clinically important response to treatment ‐ ultra short term (at 60 minutes) · people with schizophrenia It is very uncertain whether ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS changes no clinically important response to treatment ‐ ultra short term (at… compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (very low certainty). Benzodiazepines for schizophrenia (2012) · Cochrane Headline outcomes only | RR 0.07 [0, 1.13] | 1 study · 45 participants | Very low |
ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS vs PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS No clinically important response to treatment ‐ ultra short term (at 12 hours) · people with schizophrenia ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS showed no clear difference in no clinically important response to treatment ‐ ultra short term (at… compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (low certainty). Benzodiazepines for schizophrenia (2012) · Cochrane Headline outcomes only | RR 0.85 [0.51, 1.41] | 1 study · 67 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Benzodiazepines for schizophrenia 2012 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.