Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Respiratory support vs no respiratory support before cord clamping

Severe intraventricular haemorrhage · preterm infants

It is very uncertain whether respiratory support changes severe intraventricular haemorrhage grade 3 or 4 compared with no respiratory support before cord clamping (very low certainty).

1 finding from 1 review

Parent‐mediated communication intervention vs no intervention

Children's generic participation: social · children up to 5 years of age with a communication difficulty associated with any non‐progressive motor disorder acquired before 2 years…

The review found no eligible studies for this question.

1 finding from 1 review

Neuroprotection vs control

Vertical cup‐disc ratio: the proportion of participants with asymmetrical vertical cup‐disc ratio greater than 0.3 at 4 years' · people with open‐angle glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings: high‐dose urate oxidase vs low‐dose urate oxidase

Serum urate normalisation ‐ not reported · children with haematological malignancy at risk of tumour lysis syndrome

Summary of findings: high‐dose urate oxidase showed no clear difference in normalisation of serum uric acid ( compared with low‐dose urate oxidase (low certainty).

1 finding from 1 review