Summary of findings: high‐dose urate oxidase vs low‐dose urate oxidase: Serum urate normalisation ‐ not reported
Summary of findings: high‐dose urate oxidase showed no clear difference in normalisation of serum uric acid ( compared with low‐dose urate oxidase (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings: high‐dose urate oxidase vs low‐dose urate oxidase Normalisation of serum uric acid ( · children with haematological malignancy at risk of tumour lysis syndrome Summary of findings: high‐dose urate oxidase showed no clear difference in normalisation of serum uric acid ( compared with low‐dose urate oxidase (low certainty). Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer (2017) · Cochrane Headline outcomes only | RR 1.07 [0.89, 1.28] | 1 study · 29 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Urate oxidase for the prevention and treatment of tumour lysis syndrome in children with cancer 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.