Cochrane · systematic review · CD003543
Interventions to improve antibiotic prescribing practices for hospital inpatients
Davey, P, Marwick, CA, Scott, CL, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
10
No studies
1
Included studies
NR
No studies 1 · 9.1%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 27.3%Moderate 3 · 27.3%High 4 · 36.4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsEffects of interventions to improve use of antibiotics on prescribing, clinical outcomes, adverse events, and effect modifiers (heterogeneity)
Population: adults or children undergoing inpatient antibiotic prophylaxis or treatment
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of participants who were treated according to antibiotic prescribing guidelines | no estimate extracted | 29 studies · 23394 participants | High |
Duration of all antibiotic treatment | no estimate extracted | 14 studies · 3318 participants | High |
Mortality | no estimate extracted | 15827 participants | Moderate Downgraded: inconsistency, indirectness |
Mean length of hospital stay per participant | no estimate extracted | 3834 participants | Moderate Downgraded: inconsistency, indirectness |
Delay in treatment | no estimate extracted | 1 study · 2 participants | Low Downgraded: inconsistency, indirectness |
Negative professional culture | no estimate extracted | 1 participants | Low Downgraded: inconsistency, indirectness |
Effect modifier | no estimate extracted | NR | No studies |
Enablement | no estimate extracted | 29 studies · 29 participants | High |
Restriction | no estimate extracted | 29 studies · 29 participants | High |
Addition of feedback to enablement | no estimate extracted | 23 studies · 23 participants | Moderate Downgraded: inconsistency, indirectness |
Addition of enablement to restriction | no estimate extracted | 29 participants | Low Downgraded: inconsistency, indirectness |