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Evidence found and GRADE certainty

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

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No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Summary of findings: Low‐moderate GI diet vs moderate‐high GI diet (maternal outcomes)

Eclampsia · pregnant women with GDM

It is very uncertain whether summary of findings: Low‐moderate GI diet changes hypertensive disorders of pregnancy: eclampsia compared with moderate‐high GI diet (maternal outcomes) (very low certainty).

1 finding from 1 review

HALOPERIDOL vs chlorpromazine

Adverse effects ‐ cardiovascular ‐ hypotension · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effects: specific ‐ cardiovascular ‐ hypotension compared with OTHER ANTIPSYCHOTIC: b. CHLORPROMAZINE (very low certainty).

1 finding from 1 review

HALOPERIDOL vs OTHER ANTIPSYCHOTIC: f. PERPHENAZINE

Adverse effect: Specific ‐ hypotensive episode · patients with psychosis‐induced aggression or agitation

It is very uncertain whether HALOPERIDOL changes adverse effect: Specific ‐ hypotensive episode compared with OTHER ANTIPSYCHOTIC: f. PERPHENAZINE (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants with self‐reported pain intensity reduction of at least 50% from baseline · adults undergoing open heart surgery

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Number of participants with self‐reported pain intensity reduction of at least 50% from baseline · adults undergoing open heart surgery

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Number of participants below 30/100 mm on the visual analogue scale (VAS) in self‐reported postoperative pain intensity · adults undergoing open heart surgery

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Number of participants below 30/100 mm on the visual analogue scale (VAS) in self‐reported postoperative pain intensity · adults undergoing open heart surgery

It is very uncertain whether the intervention changes number of participants below 30/100 mm on the visual analogue scale… (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants with self‐reported pain intensity reduction of at least 50% from baseline · adults undergoing open heart surgery

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Number of participants below 30/100 mm on the visual analogue scale (VAS) in self‐reported postoperative pain intensity · adults undergoing open heart surgery

The review found no eligible studies for this question.

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Hypertensive disorders of pregnancy: pre‐eclampsia · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

Combined diet and exercise interventions showed no clear difference in hypertensive disorders of pregnancy (pre‐eclampsia) compared with standard care (mother) (low certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Hypertensive disorders of pregnancy (pregnancy‐induced hypertension) · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

It is very uncertain whether combined diet and exercise interventions changes hypertensive disorders of pregnancy (pregnancy‐induced… compared with standard care (mother) (very low certainty).

1 finding from 1 review

Alemtuzumab 12 mg vs interferon beta‐1a

Number of participants with new T2‐hyperintense lesions on magnetic resonance imaging · patients with relapsing‐remitting multiple sclerosis

Alemtuzumab 12 mg may leads to lower number of participants with new T2‐hyperintense lesions on magnetic… compared with interferon beta 1a (low certainty).

1 finding from 1 review