Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,245 questions · 1,274 findings · 321 reviews

No studies found 247 · 19.4%GRADE not reported 195 · 15.3%Very low 372 · 29.2%Low 282 · 22.1%Moderate 141 · 11.1%High 37 · 2.9%

Intervention not reported

Pain pressure threshold short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Disability (NDI) short term Function (NPQ) short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Quality of life (SF‐36, Functional Component) short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Intervention not reported

Pain intensity (VAS) short term · patients with chronic neck pain (pain for more than 90 days)
1 finding from 1 review

Root-end resection (with or without root-end filling; surgical retreatment) vs Non-surgical re-treatment (orthograde root canal therapy)

Prevalence of pain - 1 day · People with one or more endodontically treated teeth and a periapical condition requiring retreatment

Root-end resection (with or without root-end filling; surgical… may leads to higher prevalence of pain - 1 day (participants reporting pain) compared with root canal retreatment (non-surgical/orthograde) (low certainty).

1 finding from 1 review

Root-end resection (with or without root-end filling; surgical retreatment) vs Non-surgical re-treatment (orthograde root canal therapy)

Healing - 1 year · People with one or more endodontically treated teeth and a periapical condition requiring retreatment

It is very uncertain whether root-end resection (with or without root-end filling; surgical… changes healing - 1 year compared with root canal retreatment (non-surgical/orthograde) (very low certainty).

1 finding from 1 review

Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs (Optimised) usual care

Oral health-related quality of life · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)

The review found no eligible studies for this question.

1 finding from 1 review

Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs (Optimised) usual care

Plaque · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)

Educational intervention with information and practical components… showed no clear difference in dental plaque compared with (Optimised) usual care (low certainty).

1 finding from 1 review

Decompressive surgery plus radiotherapy vs radiotherapy

Ambulation · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…

Decompressive surgery plus radiotherapy may leads to higher ambulation Immediately after completing RT compared with radiotherapy (low certainty).

1 finding from 1 review

Decompressive surgery plus radiotherapy vs radiotherapy

Survival (short term) At 30 days · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…

Decompressive surgery plus radiotherapy showed no clear difference in survival (short term) At 30 days compared with radiotherapy (low certainty).

1 finding from 1 review

Nitrofurantoin and close surveillance vs close surveillance alone

Recurrent pyelonephritis · pregnant women with a history of one or more UTI before or during pregnancy

It is very uncertain whether nitrofurantoin and close surveillance changes recurrent pyelonephritis compared with close surveillance alone (very low certainty).

1 finding from 1 review

Nitrofurantoin and close surveillance vs close surveillance alone

Recurrent UTI (cystitis) · pregnant women with a history of one or more UTI before or during pregnancy

It is very uncertain whether nitrofurantoin and close surveillance changes recurrent UTI (cystitis) compared with close surveillance alone (very low certainty).

1 finding from 1 review

Nitrofurantoin and close surveillance vs close surveillance alone

Preterm birth · pregnant women with a history of one or more UTI before or during pregnancy

It is very uncertain whether nitrofurantoin and close surveillance changes preterm birth (< 37 weeks) compared with close surveillance alone (very low certainty).

1 finding from 1 review

Nitrofurantoin and close surveillance vs close surveillance alone

Birthweight < 2500 (g) · pregnant women with a history of one or more UTI before or during pregnancy

It is very uncertain whether nitrofurantoin and close surveillance changes birthweight < 2500 (g) compared with close surveillance alone (very low certainty).

1 finding from 1 review