Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,760 questions · 8,065 findings · 1,036 reviews

No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Intervention not reported

Grief in the relatives ICG (0 to 95; > 25 = presence of complicated grief) measured at 12 months TRIG (21 to 105; lower scores indicate higher levels of grief) measured at 3 and 9 months · relatives, patients, and healthcare professionals during resucitation
1 finding from 1 review

CBT vs TAU

AEs · chronic pain (excluding headache) in adults
2 findings from 1 review · compare the 2 reviews

Brexpiprazole vs antidepressive agents

Adverse effects: 2. Extrapyramidal ‐ akathisia · participants of any age with a primary diagnosis of major depressive disorder

Brexpiprazole probably leads to higher adverse effects: akathisia (followed up until the end of the longest compared with antidepressive agents (moderate certainty).

1 finding from 1 review

Brexpiprazole vs antidepressive agents

Weight gain · participants of any age with a primary diagnosis of major depressive disorder

Brexpiprazole probably leads to higher adverse effects: weight gain (followed up until the end of the longest compared with antidepressive agents (moderate certainty).

1 finding from 1 review

Hypothermic oxygenated perfusion (HOPE) vs static cold storage (SCS)

Ischaemic biliary complications (donated following brain death (DBD)) · liver transplant recipients

Hypothermic oxygenated perfusion (HOPE) showed no clear difference in ischaemic biliary complications (donated following brain death (DBD)) compared with static cold storage (SCS); GRADE not reported.

1 finding from 1 review

Hypothermic oxygenated perfusion (HOPE) vs static cold storage (SCS)

Ischaemic biliary complications (donated following circulatory death (DCD)) · liver transplant recipients

Hypothermic oxygenated perfusion (HOPE) led to lower ischaemic biliary complications (donated following circulatory death… compared with static cold storage (SCS); GRADE not reported.

1 finding from 1 review