Secondary caries prevention in young permanent first molars · Children with deep occlusal caries in young permanent first molars (indirect pulp capping)
SDF and RMGIC did not differ significantly for secondary caries prevention in young permanent molars (no events; p>0.05; ungraded).
1 finding from 1 review
Baraka et al. (2022): no significant difference in secondary caries prevention between 38% SDF and RMGIC (no secondary caries in either group through 12 months; p=0.63 at 12 months; overall p=0.26).
1 study · 49 participants
GRADE not reported
Oral health-related quality of life · Adolescents (10-19 years)
The umbrella review reported worse oral health-related quality of life with greater caries severity.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Oral health-related quality of life · Adolescents (10-19 years)
Oral health promotion programs have a positive effect on OHRQoL in adolescents (narrative synthesis; low methodological quality of included evidence; no pooled estimate or GRADE rating).
2 findings from 1 review
MMP-8 location/depth · Human ex vivo carious dentin
MMP-8 showed no statistical difference by lesion location; the evidence is very uncertain (very low certainty).
1 finding from 1 review
Oral health-related quality of life · Adolescents (10-19 years)
The umbrella review reported better oral health-related quality of life after completed orthodontic treatment.
1 finding from 1 review
no estimate extracted
Studies not reported
GRADE not reported
Predictive performance of the Cariogram for caries increment (negative likelihood ratio, LR-) · Children/adolescents (coronal caries) and older adults (root caries); populations from areas with varying caries risk
Modified Cariogram models showed negative likelihood ratios of about 0.5-0.61, above the useful rule-out threshold; no pooled estimate; ungraded.
1 finding from 1 review
Oral health-related quality of life · Adolescents (10-19 years)
The abstract reports older age is associated with worse OHRQoL, but the body notes the evidence on age is limited and conflicting (narrative synthesis; no pooled estimate or GRADE rating).
2 findings from 1 review
Oral-health-related quality of life in adolescents: umbrella review. 2023 All outcomesCommunity/school/clinic settings; adolescents 10-19 years; included reviews conducted in multiple countries
Worse oral health status, older age, female sex and worse socioeconomic status were significantly associated with worse OHRQoL. [Body: the influence of religion and age on OHRQoL is unknown; Biological data such as…
Studies not reported
GRADE not reported
no estimate extracted
Studies not reported
GRADE not reported
Remineralization / reduction in lesion severity (change in QLF, laser fluorescence, or lesion area) · Patients with white spot lesions / early caries lesions (WSLs/ECLs), including orthodontic and non-orthodontic lesions, active caries…
Resin infiltration did not differ significantly from P11-4 alone (SMD -0.39, 95% CI -0.97 to 0.20); certainty of evidence not assessed (no GRADE).
1 finding from 1 review
Secondary caries · Patients requiring dental restoration; deciduous (primary) teeth
Over 2 or more years in deciduous teeth, GIC probably had a higher risk of secondary caries than RMGIC (RR 1.92, 95% CI 1.03-3.56; moderate certainty).
1 finding from 1 review
new active or inactive carious lesions · Children with dental caries in permanent (first) molars
SDF had a 72% preventative fraction; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
Pulp necrosis · Vital teeth
The pooled incidence with eugenol-based temporary cement was 3.34%.
2 findings from 1 review
Proportion 3.34 [1.66, 5.58]
7043 participants
GRADE not reported
Proportion 5.77 [3.72, 8.24]
639 participants
GRADE not reported
Secondary prevention of caries · children with deep occlusal carious lesions in permanent molars
No significant difference in secondary caries prevention was reported; no effect estimate or GRADE rating was reported.
1 finding from 1 review
Body‐mass index z score (zBMI) · Children aged 1–6 years
The review reported lower body mass index-for-age z scores in children with mouth pain.
1 finding from 1 review
Root caries increment · Individuals of all ages
The review reported this model performance without meta-analysis.
22 findings from 1 review
Show 19 more findings
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Sánchez-García,2011 [23]; model performance 1
LR- 0.86 [0.80, 0.93]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Ritter,2016 [22]; model performance 3
LR− 0.48 [0.32, 0.71]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Hayes,2017 [33]; model performance 4
LR− 0.37 [0.23, 0.59]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Hayes,2017 [33]; model performance 1
LR+ 2.12 [1.71, 2.63]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Ritter,2016 [22]; model performance 3
LR+ 1.81 [1.33, 2.47]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Hayes,2017 [33]; model performance 3
LR+ 1.88 [1.53, 2.29]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Hayes,2017 [33]; model performance 2
LR− 0.35 [0.23, 0.52]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Hayes,2017 [33]; model performance 2
LR+ 2.78 [2.14, 3.62]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Hayes,2017 [33]; model performance 4
LR+ 1.88 [1.53, 2.29]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Hayes,2017 [33]; model performance 5
LR+ 2.13 [1.68, 2.69]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Ritter,2016 [22]; model performance 5
LR− 0.39 [0.26, 0.60]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Hayes,2017 [33]; model performance 1
LR− 0.34 [0.21, 0.54]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Ritter,2016 [22]; model performance 2
LR+ 2.23 [1.60, 3.10]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Hayes,2017 [33]; model performance 3
LR− 0.37 [0.23, 0.59]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Ritter,2016 [22]; model performance 1
LR+ 1.88 [1.38, 2.55]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Ritter,2016 [22]; model performance 4
LR− 0.42 [0.28, 0.64]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Sánchez-García,2011 [23]; model performance 1
LR+ 7.09 [3.29, 15.30]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Hayes,2017 [33]; model performance 5
LR− 0.41 [0.28, 0.61]
1 study
GRADE not reported
Multivariable prediction models of caries increment: a systematic review and critical appraisal. 2023 All outcomesFollow-up ≥1 year · Oral health care without geographic restriction · Ritter,2016 [22]; model performance 1
LR− 0.43 [0.29, 0.66]
1 study
GRADE not reported
Secondary caries · Patients requiring dental restoration; permanent teeth
Over 2 or more years in permanent teeth, the effect of compomer versus GIC on secondary caries is very uncertain (RR 3.20, 95% CI 0.59-17.33; very low certainty).
1 finding from 1 review
new carious lesions or fillings at tooth level · children with caries in permanent molars
SDF had a 41% preventative fraction at tooth level; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
Secondary caries · Patients requiring dental restoration; deciduous (primary) teeth
In deciduous teeth at 1 year, pooled bioactive materials (RMGIC and compomer) showed no significant difference from resin composite in secondary caries (RR 0.54, 95% CI 0.07-4.10; ungraded).
1 finding from 1 review
Dentin bridge formation · Patients with carious pulp exposure in permanent teeth undergoing partial pulpotomy
Evidence on dentin bridge formation for calcium hydroxide versus MTA is weak and imprecise, with no material shown superior (4 RCTs, not pooled; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in immature permanent teeth
In immature teeth, the effect of MTA versus calcium hydroxide on success is very uncertain (OR 2.22, 95% CI 0.13-36.67; very low certainty).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients with carious pulp exposure in permanent teeth undergoing direct pulp capping
For direct pulp capping, MTA probably achieves higher clinical and radiographic success than calcium hydroxide (OR 3.10, 95% CI 1.66-5.79; moderate certainty).
1 finding from 1 review