What do systematic reviews say?

Summary of findings table ‐ Contact immunotherapy (diphencyprone or squaric acid dibutil ester) vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Contact immunotherapy (diphencyprone or squaric acid dibutil ester) vs hair growth stimulants (minoxidil)

It is very uncertain whether summary of findings table ‐ Contact immunotherapy (diphencyprone or… changes short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of compared with hair growth stimulants (minoxidil) (very low certainty).

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  RR 1.16 [0.79, 1.71]
  1 study · 99 participants
  Very low

Summary of findings table ‐ Contact immunotherapy (diphencyprone or squaric acid dibutil ester) vs hair growth stimulants (minoxidil)

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Contact immunotherapy (diphencyprone or squaric acid dibutil ester) vs hair growth stimulants (minoxidil)

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Contact immunotherapy (diphencyprone or squaric acid dibutil ester) vs hair growth stimulants (minoxidil)

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Dietary supplements (alpha lipoic acid +/- vitamins/lycopene/green tea; hypericum; Catuama; lycopene) vs placebo

• Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes

  short-term (up to 3 months)
  SoF5 Dietary supplements vs placebo. Symptom relief short-term: insufficient or contradictory evidence regarding benefit of any evaluated dietary supplement; 628 participants (12 RCTs); very low. Subgroups: ALA without…
  12 studies · 628 participants
  Very low

Triclosan mouthwash (with and without alcohol); zinc lactate + chlorhexidine + cetylpyridinium mouthwash vs Placebo mouthwash

• Interventions for managing halitosis 2019 · Cochrane All outcomes
  Lopez Jornet 2003 (4-arm RCT) compared triclosan mouthwash with and without alcohol and a zinc lactate + chlorhexidine + cetylpyridinium mouthwash versus placebo mouthwash (VSC by halimeter and OLT). We could not…
  1 study
  GRADE not reported

Dental extraction protocol with plasma rich in growth factors (PRGF) inserted into the postextraction alveolus vs Standard dental extraction protocol without PRGF

• Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes

  24 to 60 months
  No intraoperative complications were observed in either of the groups.
  1 study · 176 participants
  GRADE not reported

Dental extraction protocol with plasma rich in growth factors (PRGF) inserted into the postextraction alveolus vs Standard dental extraction protocol without PRGF

It is very uncertain whether dental extraction protocol with plasma rich in growth factors (PRGF)… changes MRONJ (incidence proportion) compared with standard dental extraction protocol without PRGF (very low certainty).

• Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes

  24 to 60 months
  RR 0.08 [0.00, 1.51]
  1 study · 176 participants
  Very low

Different etching materials (phosphoric acid, polyacrylic acid, maleic acid, etc.), acid concentrations or etching times vs An alternative etching material, concentration or etching time

The review found no eligible studies for this question.

• Enamel etching for bonding fixed orthodontic braces 2013 · Cochrane All outcomes
  We identified no eligible trial that examined the effects of conventional etchants with respect to different etching concentrations or etching times for the bonding of fixed orthodontic appliances. No eligible RCTs…
  Studies not reported
  No studies found

Fluoride concentration relative to the acceptable range (electrometric ion-selective electrode measurement; acceptable range mostly 0.6-0.8 ppmF) vs None (descriptive proportion meta-analysis)

In the Northeast Brazilian region, a pooled 79.7% of water samples had fluoride below the acceptable range; ungraded.

• External control of fluoridation in the public water supplies of Brazilian cities as a strategy against caries: a… 2021 All outcomes

  Public water supply / water treatment stations in Brazilian cities (external control of artificial fluoridation) · Region: Northeast Brazil
  Prevalence 79.7
  Studies not reported
  GRADE not reported
• External control of fluoridation in the public water supplies of Brazilian cities as a strategy against caries: a… 2021 All outcomes

  Public water supply / water treatment stations in Brazilian cities (external control of artificial fluoridation) · Region: Southeast Brazil
  Prevalence 24.6
  Studies not reported
  GRADE not reported

Fluoride concentration relative to the acceptable range (electrometric ion-selective electrode measurement; acceptable range mostly 0.6-0.8 ppmF) vs None (descriptive proportion meta-analysis)

In the Southeast Brazilian region, a pooled 11.5% of water samples had fluoride above the acceptable range; ungraded.

• External control of fluoridation in the public water supplies of Brazilian cities as a strategy against caries: a… 2021 All outcomes

  Public water supply / water treatment stations in Brazilian cities (external control of artificial fluoridation) · Region: Southeast Brazil
  Prevalence 11.5
  Studies not reported
  GRADE not reported
• External control of fluoridation in the public water supplies of Brazilian cities as a strategy against caries: a… 2021 All outcomes

  Public water supply / water treatment stations in Brazilian cities (external control of artificial fluoridation) · Region: Northeast Brazil
  Prevalence 0.2
  Studies not reported
  GRADE not reported

Fluoride concentration relative to the acceptable range (electrometric ion-selective electrode measurement; acceptable range mostly 0.6-0.8 ppmF) vs None (descriptive proportion meta-analysis)

In Brazilian cities using external control, more than half of artificially fluoridated public water supply samples (pooled 56.6%, 95% CI 45.5 to 67.3) had fluoride concentrations outside the acceptable range, with very high heterogeneity (I2=99.5%); ungraded.

• External control of fluoridation in the public water supplies of Brazilian cities as a strategy against caries: a… 2021 All outcomes

  Public water supply / water treatment stations in Brazilian cities (external control of artificial fluoridation)
  Prevalence 56.6 [45.5, 67.3]
  12 studies
  GRADE not reported
• External control of fluoridation in the public water supplies of Brazilian cities as a strategy against caries: a… 2021 All outcomes

  Public water supply / water treatment stations in Brazilian cities (external control of artificial fluoridation) · Region: Southeast Brazil
  Prevalence 42.4 [30.9, 54.4]
  Studies not reported
  GRADE not reported
• External control of fluoridation in the public water supplies of Brazilian cities as a strategy against caries: a… 2021 All outcomes

  Public water supply / water treatment stations in Brazilian cities (external control of artificial fluoridation) · Region: Northeast Brazil
  Prevalence 81.1 [65.3, 92.9]
  Studies not reported
  GRADE not reported

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

The review found no eligible studies for this question.

• Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
  No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
  0 studies
  No studies found

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

The review found no eligible studies for this question.

• Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
  No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
  0 studies
  No studies found

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

The review found no eligible studies for this question.

• Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
  No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
  0 studies
  No studies found

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

The review found no eligible studies for this question.

• Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
  No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
  0 studies
  No studies found

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

The review found no eligible studies for this question.

• Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
  No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
  0 studies
  No studies found

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

The review found no eligible studies for this question.

• Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
  No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
  0 studies
  No studies found

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

The review found no eligible studies for this question.

• Interventions for managing relapse of the lower front teeth after orthodontic treatment 2013 · Cochrane All outcomes
  No RCTs met the inclusion criteria for this review. After deduplication, the electronic searching identified 527 publications; after reviewing the titles and abstracts, none focused on interventions to correct the…
  0 studies
  No studies found