Stillbirth · women at risk of preterm birth
Strategies to increase use of antenatal corticosteroids probably leads to higher stillbirth (at population level) compared with routine (usual) care (moderate certainty).
1 finding from 1 review
Stillbirth · preventing preterm birth in women with singleton pregnancy
Cerclage showed no clear difference in stillbirths compared with no cerclage (low certainty).
1 finding from 1 review
Neonatal sepsis/infection · preterm prelabour rupture of membranes (PPROM)
Planned early birth showed no clear difference in neonatal infection/sepsis compared with expectant management (moderate certainty).
1 finding from 1 review
Neonatal respiratory distress syndrome · preterm prelabour rupture of membranes (PPROM)
Planned early birth leads to higher neonatal respiratory distress syndrome compared with expectant management (high certainty).
1 finding from 1 review
Need for mechanical ventilation · preterm prelabour rupture of membranes (PPROM)
Planned early birth leads to higher need for ventilation compared with expectant management (high certainty).
1 finding from 1 review
Admission to neonatal intensive care unit · preterm prelabour rupture of membranes (PPROM)
Planned early birth probably leads to higher admission to neonatal intensive care compared with expectant management (moderate certainty).
1 finding from 1 review
Caesarean section · preterm prelabour rupture of membranes (PPROM)
Planned early birth leads to higher caesarean section compared with expectant management (high certainty).
1 finding from 1 review
Chorioamnionitis · preterm prelabour rupture of membranes (PPROM)
Planned early birth probably leads to lower chorioamnionitis compared with expectant management (moderate certainty).
1 finding from 1 review
Length of maternal hospital stay (days) · preterm prelabour rupture of membranes (PPROM)
Planned early birth showed no clear difference in length of hospital stay (maternal) compared with expectant management (moderate certainty).
1 finding from 1 review
Preterm low birthweight (below or equal 2500 g) · pregnant women presenting for routine prenatal care
Lower genital tract infection screening probably leads to lower preterm low birthweight (below or equal 2500 g) compared with no screening (moderate certainty).
1 finding from 1 review
Preterm very low birthweight (below or equal 1500 g) · pregnant women presenting for routine prenatal care
Lower genital tract infection screening probably leads to lower preterm very low birthweight (below or equal 1500 g) compared with no screening (moderate certainty).
1 finding from 1 review
Death (fetal, neonatal, or later (up to 2 years' corrected age))** · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in death (fetal, neonatal, or later (up to 2 years' corrected age))** compared with placebo (outcomes (moderate certainty).
1 finding from 1 review
Death or cerebral palsy · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in death or cerebral palsy (up to school age)** compared with placebo (outcomes (low certainty).
2 findings from 1 review
Major neurodevelopmental disability at childhood · women at risk of preterm birth (< 34 weeks' gestation)
It is very uncertain whether magnesium sulphate changes major neurodevelopmental disability (school age)** compared with placebo (outcomes (very low certainty).
1 finding from 1 review
Death or major neurodevelopmental disability · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in death or major neurodevelopmental disability (up to school age)** compared with placebo (outcomes (low certainty).
2 findings from 1 review
Severe maternal outcome potentially related to treatment (death, respiratory arrest, or cardiac arrest)** · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in severe maternal outcome potentially related to treatment (death,… compared with placebo (outcomes (low certainty).
1 finding from 1 review
Adverse effects sufficient to stop treatment · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate probably leads to higher adverse effects severe enough to stop treatment** compared with placebo (outcomes (moderate certainty).
1 finding from 1 review
Postpartum haemorrhage · women at risk of preterm birth (< 34 weeks' gestation)
Magnesium sulphate showed no clear difference in postpartum haemorrhage** compared with placebo (outcomes (moderate certainty).
1 finding from 1 review
Any breastfeeding at hospital discharge · women at risk of preterm birth (< 34 weeks' gestation)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Women’s views of treatment** · women at risk of preterm birth (< 34 weeks' gestation)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found