Findings

What do systematic reviews say?

96 questions · 99 findings · 9 reviews

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No studies found 29 · 29.3%GRADE not reported 0 · 0%Very low 29 · 29.3%Low 25 · 25.3%Moderate 16 · 16.2%High 0 · 0%

Tramadol in combination with acetaminophen vs placebo

Outcomesa · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Tramadol in combination with acetaminophen vs placebo

Pain · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 614 participants
Moderate

Tramadol in combination with acetaminophen vs placebo

Physical function · patients with osteoarthritis

1 finding from 1 review

Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 614 participants
Moderate

Music plus analgesia vs analgesia

Rescue analgesic requirement (cumulative dose) – Tramadol · post‐caesarean pain

1 finding from 1 review

Complementary and alternative therapies for post‐caesarean pain 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 70 participants
Low

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Withdrawal symptoms · management of opium withdrawal

1 finding from 1 review

Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
no estimate extracted
72 participants
Very low

Pharmacological detoxification treatment vs other pharmacological detoxification treatment

Completion of treatment · management of opium withdrawal

It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: methadone versus tramadol compared with other pharmacological detoxification treatment (very low certainty).

1 finding from 1 review

Pharmacological therapies for management of opium withdrawal 2018 · Cochrane Headline outcomes only
RR 0.95 [0.65, 1.37]
72 participants
Very low

Fentanyl vs tramadol

Major neurodevelopmental disability in children aged 3 to 5 years CA · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fentanyl vs tramadol

Cognitive and educational outcomes in children more than five years old · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fentanyl vs tramadol

All‐cause mortality during hospital stay · postoperative pain in preterm and term infants

It is very uncertain whether fentanyl changes all‐cause mortality during initial hospitalization compared with tramadol (very low certainty).

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
RR 0.99 [0.59, 1.64]
1 study · 171 participants
Very low

Fentanyl vs tramadol

Severe (defined as stage 3 or greater) retinopathy of prematurity ‐ not reported · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fentanyl vs tramadol

Severe (grade 3 or greater) intraventricular hemorrhage (IVH) on cranial ultrasound ‐ not reported · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fentanyl vs tramadol

Pain · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fentanyl vs tramadol

Major neurodevelopmental disability in children aged 18 to 24 months CA · postoperative pain in preterm and term infants

The review found no eligible studies for this question.

1 finding from 1 review

Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nalbuphine vs tramadol

Number of patients with moderate/severe pain (1 hour postoperatively) · children undergoing surgery

1 finding from 1 review

Nalbuphine for postoperative pain treatment in children 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low

Nalbuphine vs tramadol

Number of patients with the need for rescue analgesia (12 hours postoperatively) · children undergoing surgery

Nalbuphine showed no clear difference in number of patients with the need for rescue analgesia (2 hours… compared with tramadol (low certainty).

3 findings from 1 review

Nalbuphine for postoperative pain treatment in children 2014 · Cochrane Headline outcomes only
RR 0.75 [0.39, 1.43]
1 study · 76 participants
Low
Nalbuphine for postoperative pain treatment in children 2014 · Cochrane Headline outcomes only
RR 0.33 [0.04, 2.77]
1 study · 24 participants
Low
Nalbuphine for postoperative pain treatment in children 2014 · Cochrane Headline outcomes only
RR 1.45 [0.5, 4.16]
2 studies · 110 participants
Low

Nalbuphine vs tramadol

Number of patients with postoperative nausea and vomiting (24 hours postoperatively) · children undergoing surgery

Nalbuphine showed no clear difference in number of patients with postoperative nausea and vomiting (24 hours… compared with tramadol (low certainty).

1 finding from 1 review

Nalbuphine for postoperative pain treatment in children 2014 · Cochrane Headline outcomes only
RR 0.5 [0.11, 2.23]
1 study · 24 participants
Low