Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

108 questions · 109 findings · 17 reviews · Pain, Palliative and Supportive Care

No studies found 16 · 14.7%GRADE not reported 5 · 4.6%Very low 54 · 49.5%Low 9 · 8.3%Moderate 10 · 9.2%High 15 · 13.8%

Intervention not reported

At least 50% of maximum pain relief over 4 to 6 hours · Adults with acute pain

The intervention leads to higher at least 50% of maximum pain relief over 4 to 6 hours (high certainty).

1 finding from 1 review

Intervention not reported

Participants remedicating within 8 hours · Adults with acute pain

The intervention leads to lower participants remedicating within 8 hours (high certainty).

1 finding from 1 review

Intervention not reported

Participants with at least 1 adverse event (all diclofenac potassium doses, 25 mg to 100 mg) · Adults with acute pain

The intervention showed no clear difference in participants with at least 1 adverse event (all diclofenac potassium… (moderate certainty).

1 finding from 1 review

Intervention not reported

At least 50% of maximum pain relief over 4 to 6 h · adults with moderate or severe acute postoperative pain

The intervention leads to higher at least 50% of maximum pain relief over 4 to 6 h (high certainty).

1 finding from 1 review

Intervention not reported

Participants with at least 1 adverse event · adults with moderate or severe acute postoperative pain

The intervention showed no clear difference in participants with at least 1 adverse event (moderate certainty).

1 finding from 1 review

Intervention not reported

At least 50% of maximum pain relief over 4 to 6 h · Adults with acute pain

The intervention probably leads to higher at least 50% of maximum pain relief over 4 to 6 h (moderate certainty).

1 finding from 1 review