Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

339 questions · 355 findings · 25 reviews

No studies found 134 · 37.7%GRADE not reported 38 · 10.7%Very low 87 · 24.5%Low 66 · 18.6%Moderate 27 · 7.6%High 3 · 0.8%

Primary outcome: topical local anaesthetics vs placebo or no treatment

Postoperative pain or distress · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Lip or cheek biting · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Intraoperative or postoperative bleeding · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Parental satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Primary outcome: topical local anaesthetics vs placebo or no treatment

Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Subdiaphragmatic intraperitoneal local anaesthetic vs control

Incidence of STP at 24 hours post‐operatively · women undergoing a diagnostic or operative laparoscopic gynaecological procedure

Subdiaphragmatic intraperitoneal local anaesthetic showed no clear difference in incidence of STP at 24 hours post‐operatively compared with control (moderate certainty).

1 finding from 1 review

Local anaesthetic to peritoneal cavity (not subdiaphragmatic) vs control

Incidence of STP within 4‐8 hours post‐operatively · women undergoing gynaecological laparoscopic procedures

Local anaesthetic to peritoneal cavity (not subdiaphragmatic) may leads to lower incidence of STP within 4‐8 hours post‐operatively compared with control (low certainty).

1 finding from 1 review