Findings

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Evidence found and GRADE certainty

4,749 questions · 14,261 findings · 832 reviews

No studies found 3,655 · 25.6%GRADE not reported 2,111 · 14.8%Very low 3,646 · 25.6%Low 3,028 · 21.2%Moderate 1,501 · 10.5%High 320 · 2.2%

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Partial oral treatment vs conventional intravenous treatment of endocarditis on the left side of the heart (on native or prosthetic valves) and bacteraemia

Need for cardiac surgical interventions · people with endocarditis on the left side of the heart (on native or prosthetic valves) with bacteraemia for Streptococcus, Enterococcus…

It is very uncertain whether partial oral treatment changes need for cardiac surgicalinterventions compared with conventional intravenous treatment of endocarditis on the left side… (very low certainty).

1 finding from 1 review

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Discomfort/pain · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances

Light vibrational forces (LVF) showed no clear difference in patient perception of pain and discomfort (VAS 0 to 100 mm),… compared with conventional orthodontic appliance treatment (placebo or no adjunct) (low certainty).

1 finding from 1 review

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Patient-reported need for analgesics · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances

Light vibrational forces (LVF) showed no clear difference in patient-reported need for analgesics during first week of initial… compared with conventional orthodontic appliance treatment (placebo or no adjunct) (low certainty).

1 finding from 1 review

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Harms: non-serious adverse effects (headache, discomfort, loosening of temporary anchorage devices) · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances

Light vibrational forces (LVF) showed no clear difference in harms: non-serious adverse effects (headache, discomfort, loosening… compared with conventional orthodontic appliance treatment (placebo or no adjunct); GRADE not reported.

1 finding from 1 review

Brief intervention vs brief advice, information, or assessment only

Harmful alcohol use · people with hazardous or harmful alcohol consumption
2 findings from 1 review

Dietary advice on how to achieve a healthy diet for infants (tailored advice focused on a diet low in saturated fat and cholesterol intake) vs usual care

Dental caries · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…

The review found no eligible studies for this question.

2 findings from 1 review