Cochrane · systematic review · CD013610

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis

Jones, M, Moffatt, F, Harvey, A, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
28
current version
GRADE rated
11
No studies
17
Included studies
NR
No studies 17 · 60.7%Ungraded 0 · 0%Very low 11 · 39.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music versus no music

Population: people with CF
7 questions
OutcomeEffectEvidenceStatus / GRADE
Adherence to treatment Morisky‐Green questionnaire (number of participants showing full adherence)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music
RR 1.56 [1.01, 2.4]1 study · 30 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Frequency of hospitalisation for respiratory infection
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music
RR 0.17 [0.02, 1.22]1 study · 30 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Frequency of non‐hospitalised respiratory infection
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music
no estimate extractedNRNo studies
FEV1 % predicted (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music
no estimate extractedNRNo studies
FVC % predicted (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music
no estimate extractedNRNo studies
QoL (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music
no estimate extractedNRNo studies
Exercise capacity (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music
no estimate extractedNRNo studies

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ self‐selected music versus no music

Population: people with CF
7 questions
OutcomeEffectEvidenceStatus / GRADE
Adherence to treatment Morisky‐Green questionnaire (number of participants showing full adherence)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ self‐selected music vs no music
RR 1.03 [0.57, 1.86]1 study · 28 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Frequency of hospitalisation for respiratory infection
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ self‐selected music vs no music
RR 0.58 [0.18, 1.86]1 study · 28 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Frequency of non‐hospitalised respiratory infection
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ self‐selected music vs no music
no estimate extractedNRNo studies
FEV1 % predicted (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ self‐selected music vs no music
no estimate extractedNRNo studies
FVC % predicted (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ self‐selected music vs no music
no estimate extractedNRNo studies
QoL (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ self‐selected music vs no music
no estimate extractedNRNo studies
Exercise capacity (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ self‐selected music vs no music
no estimate extractedNRNo studies

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music versus self‐selected music

Population: people with CF
7 questions
OutcomeEffectEvidenceStatus / GRADE
Adherence to treatment Morisky‐Green questionnaire (number of participants showing full adherence)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs self‐selected music
RR 1.52 [0.97, 2.38]1 study · 28 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Frequency of hospitalisation for respiratory infection
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs self‐selected music
RR 0.29 [0.03, 2.45]1 study · 28 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Frequency of non‐hospitalised respiratory infection
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs self‐selected music
no estimate extractedNRNo studies
FEV1 % predicted (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs self‐selected music
no estimate extractedNRNo studies
FVC % predicted (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs self‐selected music
no estimate extractedNRNo studies
QoL (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs self‐selected music
no estimate extractedNRNo studies
Exercise capacity (change from baseline)
Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs self‐selected music
no estimate extractedNRNo studies

Educational interventions to improve adherence to exercise for people with CF

Population: people with CF
7 questions
OutcomeEffectEvidenceStatus / GRADE
Adherence to treatment (number of participants undertaking physical activity)
RR 3.67 [1.24, 10.85]1 study · 34 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Frequency of hospitalisation for respiratory infection
no estimate extractedNRNo studies
Frequency of non‐hospitalised respiratory infection
no estimate extractedNRNo studies
FEV1 % predicted (change from baseline)
no estimate extracted1 study · 34 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
FVC % predicted (change from baseline)
no estimate extracted1 study · 34 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
QoL (change from baseline)
no estimate extracted1 study · 34 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Exercise capacity (change from baseline) VO2 peak
no estimate extracted1 study · 34 participantsVery low
Downgraded: risk of bias, imprecision, indirectness