Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

173 questions · 180 findings · 26 reviews · Headline outcomes only

No studies found 33 · 18.3%GRADE not reported 9 · 5%Very low 35 · 19.4%Low 58 · 32.2%Moderate 33 · 18.3%High 12 · 6.7%

Single‐dose antibiotic vs short duration antibiotics

Preterm delivery ‐ Same antimicrobial agent only · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic showed no clear difference in preterm delivery ‐ Same antimicrobial agent only compared with short‐course (four‐ to seven‐day) antibiotic (moderate certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Same antimicrobial agent ‐ No cure (good quality studies) · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic leads to higher same antimicrobial agent ‐ No cure (good quality studies) compared with short‐course (four‐ to seven‐day) antibiotic (high certainty).

1 finding from 1 review

Single‐dose antibiotic vs short duration antibiotics

Different antimicrobial agents ‐ No cure (good quality studies) · patients with asymptomatic bacteriuria during pregnancy

Single‐dose antibiotic showed no clear difference in different antimicrobial agents ‐ No cure (good quality studies) compared with short‐course (four‐ to seven‐day) antibiotic (low certainty).

1 finding from 1 review

Bathing of the critically ill with chlorhexidine vs bathing with soap and water or non‐antimicrobial washcloths

Mortality (ICU, hospital) (days) · critically ill patients

It is very uncertain whether bathing of the critically ill with chlorhexidine changes mortality Data collected (where reported) in hospital, in the ICU,… compared with bathing with soap and water or non‐antimicrobial washcloths (very low certainty).

1 finding from 1 review