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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
2,653 questions in 194 reviews · Gynaecology and Fertility
current versionsNo studies 531 · 20%Ungraded 76 · 2.9%Very low 826 · 31.1%Low 855 · 32.2%Moderate 341 · 12.9%High 24 · 0.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Ascorbic acid vs no treatment to reduce blood loss during myomectomy Blood loss (ml) Estimated blood loss during myomectomy · Women with fibroids Interventions to reduce haemorrhage during myomectomy for fibroids (2014) · Cochrane | no estimate extracted | 1 study · 102 participants | Low |
Ascorbic acid vs no treatment to reduce blood loss during myomectomy Need for blood transfusion Participants who received blood transfusion · Women with fibroids Interventions to reduce haemorrhage during myomectomy for fibroids (2014) · Cochrane | OR 0.38 [0.11, 1.32] | 1 study · 104 participants | Very low |
Ascorbic acid vs no treatment to reduce blood loss during myomectomy Duration of surgery (min) Operative time · Women with fibroids Interventions to reduce haemorrhage during myomectomy for fibroids (2014) · Cochrane | no estimate extracted | 1 study · 102 participants | Low |
Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment Misoprostol in laparoscopic myomectomy · Women with fibroids Interventions to reduce haemorrhage during myomectomy for fibroids (2014) · Cochrane | no estimate extracted | 1 study · 64 participants | Moderate |
Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment Vasopressin · Women with fibroids Interventions to reduce haemorrhage during myomectomy for fibroids (2014) · Cochrane | no estimate extracted | 3 studies · 128 participants | Moderate |
Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment Bupivicaine plus epinephrine · Women with fibroids Interventions to reduce haemorrhage during myomectomy for fibroids (2014) · Cochrane | no estimate extracted | 1 study · 60 participants | Low |
Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment Intravenous injection of tranexamic acid · Women with fibroids Interventions to reduce haemorrhage during myomectomy for fibroids (2014) · Cochrane | no estimate extracted | 1 study · 100 participants | Low |
Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment Gelatin‐thrombin matrix · Women with fibroids Interventions to reduce haemorrhage during myomectomy for fibroids (2014) · Cochrane | no estimate extracted | 1 study · 50 participants | Low |
Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment Ascorbic acid · Women with fibroids Interventions to reduce haemorrhage during myomectomy for fibroids (2014) · Cochrane | no estimate extracted | 1 study · 102 participants | Low |
Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment Dinoprostone (prostaglandin E2 analogue) · Women with fibroids Interventions to reduce haemorrhage during myomectomy for fibroids (2014) · Cochrane | no estimate extracted | 1 study · 108 participants | Low |
Cyst aspiration vs conservative management Live birth rate · women with subfertility Ovarian cyst aspiration prior to in vitro fertilization treatment for subfertility (2014) · Cochrane | no estimate extracted | NR | No studies |
Cyst aspiration vs conservative management Adverse events rate · women with subfertility Ovarian cyst aspiration prior to in vitro fertilization treatment for subfertility (2014) · Cochrane | no estimate extracted | NR | No studies |
Cyst aspiration vs conservative management Clinical pregnancy rate Ultrasound diagnosis of intrauterine pregnancy · women with subfertility Ovarian cyst aspiration prior to in vitro fertilization treatment for subfertility (2014) · Cochrane | OR 1.19 [0.33, 4.29] | 2 studies · 159 participants | Very low |
Cyst aspiration vs conservative management Number of follicles recruited Ultrasound diagnosis · women with subfertility Ovarian cyst aspiration prior to in vitro fertilization treatment for subfertility (2014) · Cochrane | no estimate extracted | 2 studies · 159 participants | Very low |
Cyst aspiration vs conservative management Number of oocytes collected Transvaginal oocyte aspiration · women with subfertility Ovarian cyst aspiration prior to in vitro fertilization treatment for subfertility (2014) · Cochrane | no estimate extracted | 3 studies · 339 participants | Low |
Cyst aspiration vs conservative management Cancellation rate per cycle · women with subfertility Ovarian cyst aspiration prior to in vitro fertilization treatment for subfertility (2014) · Cochrane | OR 0.99 [0.42, 2.33] | 1 study · 122 participants | Very low |
Exercise vs control Change in hot flushes/night sweats Self‐report1 · women with vasomotor menopausal symptoms Exercise for vasomotor menopausal symptoms (2014) · Cochrane | no estimate extracted | 3 studies · 454 participants | Low |
Exercise vs yoga Change in hot flushes/night sweats Self‐report · women with vasomotor menopausal symptoms Exercise for vasomotor menopausal symptoms (2014) · Cochrane | no estimate extracted | 2 studies · 279 participants | Low |
More vs less bed rest Ongoing pregnancy rate per randomised woman Post‐embryo transfer interventions for assisted reproduction technology cycles (2014) · Cochrane | OR 0.88 [0.6, 1.31] | 2 studies · 542 participants | Low |
More vs less bed rest Clinical pregnancy rate per randomised woman Post‐embryo transfer interventions for assisted reproduction technology cycles (2014) · Cochrane | OR 0.88 [0.6, 1.31] | 2 studies · 542 participants | Low |
Fibrin sealant vs usual care Clinical pregnancy rate per randomised woman Post‐embryo transfer interventions for assisted reproduction technology cycles (2014) · Cochrane | OR 0.98 [0.54, 1.78] | 1 study · 211 participants | Very low |
Mechanical pressure vs usual care Clinical pregnancy rate per randomised woman Post‐embryo transfer interventions for assisted reproduction technology cycles (2014) · Cochrane | OR 1.92 [1.4, 2.63] | 1 study · 639 participants | Very low |
Human chorionic gonadotrophin vs no ovulation trigger Live birth rate Live fetus delivered beyond 20 completed weeks' gestation · women with anovulatory infertility undergoing ovulation induction with clomiphene citrate Ovulation triggers in anovulatory women undergoing ovulation induction (2014) · Cochrane | OR 0.97 [0.52, 1.83] | 305 participants | Low |
Human chorionic gonadotrophin vs no ovulation trigger Ovulation rate Ultrasound evidence of collapsed follicle or mid‐luteal serum progesterone < 10 ng/mL · women with anovulatory infertility undergoing ovulation induction with clomiphene citrate Ovulation triggers in anovulatory women undergoing ovulation induction (2014) · Cochrane | OR 0.99 [0.36, 2.77] | 305 participants | Low |
Human chorionic gonadotrophin vs no ovulation trigger Clinical pregnancy rate Ultrasound evidence of pregnancy · women with anovulatory infertility undergoing ovulation induction with clomiphene citrate Ovulation triggers in anovulatory women undergoing ovulation induction (2014) · Cochrane | OR 1.02 [0.56, 1.89] | 305 participants | Low |
Human chorionic gonadotrophin vs no ovulation trigger Miscarriage rate per clinical pregnancy Spontaneous pregnancy loss before 20 weeks' gestation · women with anovulatory infertility undergoing ovulation induction with clomiphene citrate Ovulation triggers in anovulatory women undergoing ovulation induction (2014) · Cochrane | OR 1.19 [0.17, 8.23] | 54 participants | Low |
hCG vs LH surge Live birth rate per couple · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1 [0.06, 18.08] | 1 study · 24 participants | Very low |
Short interval vs long interval Pregnancy rate per couple ‐ 24 hours versus 34 to 36 hours · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 0.55 [0.31, 0.98] | 2 studies · 234 participants | Low |
Short interval vs long interval Pregnancy rate per couple ‐ 24 hours versus 48 hours · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 0.44 [0.1, 1.92] | 1 study · 30 participants | Low |
Short interval vs long interval Pregnancy rate per couple ‐ 34 to 36 hours versus 48 hours · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 0.58 [0.14, 2.48] | 1 study · 30 participants | Low |
Short interval vs long interval Miscarriage rate per pregnancy ‐ 24 hours versus 34 to 36 hours · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.58 [0.35, 7.16] | 2 studies · 67 participants | Very low |
Short interval vs long interval Miscarriage rate per pregnancy ‐ 24 hours versus 48 hours · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 4 [0.27, 58.56] | 1 study · 15 participants | Very low |
Short interval vs long interval Miscarriage rate per pregnancy ‐ 34 to 36 hours versus 48 hours · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.33 [0.07, 25.91] | 1 study · 16 participants | Very low |
hCG vs GnRH‐a Live birth rate per couple · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.04 [0.42, 2.56] | 3 studies · 104 participants | Low |
hCG vs GnRH‐a Pregnancy rate per couple · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.14 [0.63, 2.08] | 4 studies · 206 participants | Low |
hCG vs GnRH‐a Multiple pregnancy rate per pregnancy · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 0.15 [0.02, 1.38] | 4 studies · 74 participants | Very low |
hCG vs GnRH‐a Miscarriage rate per pregnancy · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.72 [0.48, 6.2] | 4 studies · 74 participants | Very low |
hCG vs LH surge Pregnancy rate per couple · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.33 [0.72, 2.45] | 4 studies · 275 participants | Low |
hCG vs GnRH‐a OHSS per cycle · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 2.27 [0.65, 7.91] | 3 studies · 456 participants | Low |
Early hCG vs late hCG Pregnancy rate per couple · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.32 [0.77, 2.25] | 1 study · 612 participants | Low |
Early hCG vs late hCG Miscarriage rate · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 0.51 [0.08, 3.28] | 1 study · 65 participants | Very low |
Intervention NR Pregnancy rate per couple · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.38 [0.28, 6.71] | 1 study · 66 participants | Very low |
hCG vs LH surge Multiple pregnancy rate per pregnancy · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.12 [0.17, 7.6] | 2 studies · 42 participants | Very low |
u‐hCG vs r‐hCG Live birth rate per couple · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.17 [0.68, 2.03] | 1 study · 284 participants | Low |
u‐hCG vs r‐hCG Pregnancy rate per couple · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 1.02 [0.65, 1.57] | 2 studies · 409 participants | Low |
u‐hCG vs r‐hCG Multiple pregnancy rate per pregnancy · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 0.99 [0.4, 2.47] | 2 studies · 109 participants | Low |
u‐hCG vs r‐hCG Miscarriage rate per pregnancy · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 0.57 [0.13, 2.47] | 2 studies · 109 participants | Very low |
u‐hCG vs r‐hCG OHSS rate per cycle · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | no estimate extracted | 2 studies · 468 participants | Moderate |
Short interval vs long interval Live birth rate per couple ‐ 24 hours versus 34 to 36 hours · women undergoing intrauterine insemination Synchronised approach for intrauterine insemination in subfertile couples (2014) · Cochrane | OR 0.52 [0.27, 1] | 1 study · 204 participants | Low |
Laparoscopy vs open appendicectomy Diagnosis before discharge · women of childbearing age with acute lower abdominal pain Laparoscopy for the management of acute lower abdominal pain in women of childbearing age (2014) · Cochrane | OR 4.1 [2.5, 6.71] | 7 studies · 561 participants | Moderate |