Cochrane · systematic review · CD006900
Ovulation triggers in anovulatory women undergoing ovulation induction
George, K, Kamath, MS, Nair, R, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 4 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Human chorionic gonadotrophin versus no ovulation trigger in clomiphene‐induced cycles
Population: women with anovulatory infertility undergoing ovulation induction with clomiphene citrate
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth rate Live fetus delivered beyond 20 completed weeks' gestation Human chorionic gonadotrophin vs no ovulation trigger | OR 0.97 [0.52, 1.83] | 305 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Ovulation rate Ultrasound evidence of collapsed follicle or mid‐luteal serum progesterone < 10 ng/mL Human chorionic gonadotrophin vs no ovulation trigger | OR 0.99 [0.36, 2.77] | 305 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Clinical pregnancy rate Ultrasound evidence of pregnancy Human chorionic gonadotrophin vs no ovulation trigger | OR 1.02 [0.56, 1.89] | 305 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Miscarriage rate per clinical pregnancy Spontaneous pregnancy loss before 20 weeks' gestation Human chorionic gonadotrophin vs no ovulation trigger | OR 1.19 [0.17, 8.23] | 54 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |