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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.
75,239 questions in 5,342 reviews
current versionsNo studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mindfulness‐enhanced parent training vs no‐treatment, waitlist, or attentional control Parenting stress; postintervention · parents of children between the ages of 0 and 18 years Mindfulness‐enhanced parenting programmes for improving the psychosocial outcomes of children (0 to 18… (2024) · Cochrane | no estimate extracted | 2 studies · 112 participants | Very low |
Mindfulness‐enhanced parent training vs no‐treatment, waitlist, or attentional control Parent mindfulness; postintervention · parents of children between the ages of 0 and 18 years Mindfulness‐enhanced parenting programmes for improving the psychosocial outcomes of children (0 to 18… (2024) · Cochrane | no estimate extracted | 3 studies · 515 participants | Very low |
Mindfulness‐enhanced parent training vs no‐treatment, waitlist, or attentional control Measures of self‐compassion · parents of children between the ages of 0 and 18 years Mindfulness‐enhanced parenting programmes for improving the psychosocial outcomes of children (0 to 18… (2024) · Cochrane | no estimate extracted | NR | No studies |
Mindfulness‐enhanced parent training vs parent training Child emotional and behavioural adjustment; postintervention · parents of children between the ages of 0 and 18 years Mindfulness‐enhanced parenting programmes for improving the psychosocial outcomes of children (0 to 18… (2024) · Cochrane | no estimate extracted | 5 studies · 203 participants | Very low |
Mindfulness‐enhanced parent training vs parent training Adverse effects · parents of children between the ages of 0 and 18 years Mindfulness‐enhanced parenting programmes for improving the psychosocial outcomes of children (0 to 18… (2024) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR All‐cause mortality · participants with gallstone disease (cholesterol, pigment, or mixed) Modified dietary fat intake for treatment of gallstone disease in people of any age (2024) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Serious adverse events at longest · participants with gallstone disease (cholesterol, pigment, or mixed) Modified dietary fat intake for treatment of gallstone disease in people of any age (2024) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Health‐related quality of life · participants with gallstone disease (cholesterol, pigment, or mixed) Modified dietary fat intake for treatment of gallstone disease in people of any age (2024) · Cochrane | no estimate extracted | NR | No studies |
Infliximab vs placebo Clinical relapse (at 30‐32 weeks, CDAI > 150) · patients with Crohn's disease (mixed disease activity population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.73 [0.63, 0.84] | 2 studies · 408 participants | Moderate |
Infliximab vs purine analogues Loss of clinical response · Crohn's disease patients (in remission at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | no estimate extracted | NR | No studies |
Infliximab vs purine analogues Withdrawal due to adverse events · Crohn's disease patients (in remission at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | no estimate extracted | NR | No studies |
Infliximab vs purine analogues Serious adverse events (at 2 years) · Crohn's disease patients (in remission at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.79 [0.37, 1.68] | 1 study · 140 participants | Very low |
Infliximab vs biosimilar Clinical relapse (at 52 weeks, HBI > 4) · patients with Crohn's disease (with mixed/low disease activity at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 1.18 [0.82, 1.69] | 1 study · 155 participants | Low |
Infliximab vs biosimilar Loss of clinical response (at 52 weeks, HBI change from baseline of less than 4 points and a total score of less than 7 points) · patients with Crohn's disease (with mixed/low disease activity at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 1.5 [1.01, 2.23] | 1 study · 155 participants | Low |
Infliximab vs biosimilar Withdrawal due to adverse events (at 52 weeks) · patients with Crohn's disease (with mixed/low disease activity at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 20.73 [2.86, 150.33] | 1 study · 155 participants | Low |
Infliximab vs biosimilar Serious adverse events (at 52 weeks) · patients with Crohn's disease (with mixed/low disease activity at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.99 [0.39, 2.5] | 1 study · 155 participants | Low |
Subcutaneous CT‐P13 and purine analogues vs intravenous CT‐P13 and purine analogues Clinical relapse (at 22 weeks, CDAI > 150) · patients with Crohn's disease (active disease population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 1.01 [0.65, 1.57] | 1 study · 53 participants | Very low |
Subcutaneous CT‐P13 and purine analogues vs intravenous CT‐P13 and purine analogues Loss of clinical response (at 22 weeks, less than 100 points in CDAI change) · patients with Crohn's disease (active disease population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.94 [0.7, 1.25] | 1 study · 53 participants | Very low |
Subcutaneous CT‐P13 and purine analogues vs intravenous CT‐P13 and purine analogues Withdrawal due to adverse events (at 30 weeks) · patients with Crohn's disease (active disease population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.77 [0.3, 1.97] | 1 study · 53 participants | Very low |
Infliximab vs placebo Loss of clinical response (at 32 weeks, less than 70 points in CDAI change) · patients with Crohn's disease (mixed disease activity population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.59 [0.37, 0.96] | 1 study · 73 participants | Very low |
Subcutaneous CT‐P13 and purine analogues vs intravenous CT‐P13 and purine analogues Serious adverse events · patients with Crohn's disease (active disease population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | no estimate extracted | NR | No studies |
Infliximab vs adalimumab Clinical relapse · patients with Crohn's disease (active disease population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | no estimate extracted | NR | No studies |
Infliximab vs adalimumab Loss of clinical response (at 56 weeks, less than 100 points in CDAI change) · patients with Crohn's disease (active disease population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.68 [0.29, 1.59] | 1 study · 73 participants | Very low |
Infliximab vs adalimumab Withdrawal due to adverse events (at 56 weeks) · patients with Crohn's disease (active disease population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.1 [0.01, 0.72] | 1 study · 73 participants | Very low |
Infliximab vs adalimumab Serious adverse events (at 56 weeks) · patients with Crohn's disease (active disease population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.09 [0.01, 1.54] | 1 study · 73 participants | Very low |
Infliximab vs placebo Withdrawal due to adverse events (at 32‐54 weeks) · patients with Crohn's disease (mixed disease activity population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.66 [0.37, 1.19] | 2 studies · 355 participants | Very low |
Infliximab vs placebo Serious adverse events (at 54 weeks) · patients with Crohn's disease (mixed disease activity population with clinical response at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.6 [0.36, 1] | 1 study · 282 participants | Very low |
Infliximab combined with purine analogues vs purine analogues Clinical relapse (at 48 weeks, CDAI of 150 or greater together with an increase in CDAImore than 70 points above baseline over 2 consecutive weeks or definitive clinical relapse requiring immediate intervention, as judged by the treating physician) · Crohn's disease patients (in remission at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.2 [0.1, 0.42] | 1 study · 115 participants | Moderate |
Infliximab combined with purine analogues vs purine analogues Loss of clinical response · Crohn's disease patients (in remission at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | no estimate extracted | NR | No studies |
Infliximab combined with purine analogues vs purine analogues Withdrawal due to adverse events (at 48 weeks) · Crohn's disease patients (in remission at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 0.47 [0.15, 1.49] | 1 study · 115 participants | Very low |
Infliximab combined with purine analogues vs purine analogues Serious adverse events (at 48 weeks to 2 years) · Crohn's disease patients (in remission at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | RR 1.19 [0.54, 2.64] | 2 studies · 257 participants | Very low |
Infliximab vs purine analogues Clinical relapse · Crohn's disease patients (in remission at baseline) Infliximab for maintenance of medically‐induced remission in Crohn's disease (2024) · Cochrane | no estimate extracted | NR | No studies |
ORT‐based algorithm vs standard starting dose of FSH Live birth or ongoing pregnancy · women undergoing IVF/ICSI Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | OR 1.12 [0.98, 1.29] | 7 studies · 4400 participants | Low |
Anticipated normal responders: higher vs lower dose of FSH IU vs 150 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | no estimate extracted | 1 study · 37 participants | Ungraded |
Anticipated high responders: higher vs lower dose of FSH IU vs 100 IU · women undergoing IVF/ICSI who are anticipated to have a hyper‐response to stimulation based on at least one ORT measure Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | OR 0.98 [0.66, 1.46] | 1 study · 521 participants | Low |
ORT‐based algorithm vs standard starting dose of FSH OHSS · women undergoing IVF/ICSI Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | OR 0.74 [0.42, 1.28] | 5 studies · 2724 participants | Low |
ORT‐based algorithm vs standard starting dose of FSH Clinical pregnancy · women undergoing IVF/ICSI Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | OR 1.04 [0.91, 1.18] | 7 studies · 4400 participants | Low |
Anticipated low responders: higher vs lower dose of FSH 300/450 IU vs 150 IU · women undergoing IVF/ICSI who are anticipated to have a low response to stimulation based on one or more ORT measure Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | OR 1.2 [0.78, 1.86] | 3 studies · 538 participants | Low |
Anticipated low responders: higher vs lower dose of FSH 400/450 IU vs 300 IU · women undergoing IVF/ICSI who are anticipated to have a low response to stimulation based on one or more ORT measure Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | OR 0.77 [0.19, 3.19] | 1 study · 62 participants | Low |
Anticipated low responders: higher vs lower dose of FSH IU vs 450 IU · women undergoing IVF/ICSI who are anticipated to have a low response to stimulation based on one or more ORT measure Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | OR 1.33 [0.71, 2.52] | 1 study · 356 participants | Low |
Anticipated normal responders: higher vs lower dose of FSH IU vs 100 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | OR 0.88 [0.57, 1.36] | 2 studies · 522 participants | Low |
Anticipated normal responders: higher vs lower dose of FSH 225/200 IU vs 150 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | OR 0.98 [0.7, 1.36] | 2 studies · 686 participants | Low |
Anticipated normal responders: higher vs lower dose of FSH IU vs 225 IU · women undergoing IVF/ICSI who are anticipated to have a normal response to stimulation based on at least one ORT measure Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro… (2024) · Cochrane | OR 0.65 [0.32, 1.32] | 1 study · 135 participants | Low |
nHFV vs invasive respiratory therapy Mortality before hospital discharge · preterm infants with respiratory distress Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress (2024) · Cochrane | RR 0.67 [0.2, 2.18] | 1 study · 80 participants | Very low |
nHFV vs nCPAP used Death or chronic lung disease · newborn (term* and preterm) infants with respiratory distress for initial respiratory support Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress (2024) · Cochrane | RR 2.5 [0.52, 12.01] | 1 study · 68 participants | Low |
nHFV vs nCPAP used Intraventricular haemorrhage, Papile grade 3/4 · newborn (term* and preterm) infants with respiratory distress for initial respiratory support Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress (2024) · Cochrane | RR 1.17 [0.36, 3.78] | 4 studies · 531 participants | Low |
nHFV vs nCPAP used Neurodevelopmental disability · newborn (term* and preterm) infants with respiratory distress for initial respiratory support Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress (2024) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
nHFV vs nIPPV used Mortality before hospital discharge · preterm infants with respiratory distress for initial respiratory support Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress (2024) · Cochrane | RR 1.86 [0.9, 3.83] | 2 studies · 84 participants | Low |
nHFV vs nIPPV used Endotracheal intubation To discharge · preterm infants with respiratory distress for initial respiratory support Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress (2024) · Cochrane | RR 1.33 [0.76, 2.34] | 5 studies · 228 participants | Low |
nHFV vs nIPPV used Chronic lung disease · preterm infants with respiratory distress for initial respiratory support Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress (2024) · Cochrane | RR 0.63 [0.42, 0.95] | 5 studies · 307 participants | Low |