Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,271 questions · 1,326 findings · 329 reviews

No studies found 247 · 18.6%GRADE not reported 237 · 17.9%Very low 379 · 28.6%Low 285 · 21.5%Moderate 141 · 10.6%High 37 · 2.8%

ARP with alloplast vs ARP with xenograft

Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with alloplast changes changes in bucco-lingual/palatal width of alveolar ridge (mm) compared with ARP with xenograft (very low certainty).

1 finding from 1 review

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with demineralised bone matrix, single particle size changes changes in bucco-lingual/palatal width of alveolar ridge (mm) compared with ARP with demineralised bone matrix, multiple particle size (very low certainty).

1 finding from 1 review

Less frequent tooth brushing (< twice daily) vs More frequent tooth brushing (>= twice daily)

Dental caries · Healthy children and adolescents in the United Arab Emirates

More frequent tooth brushing was generally protective against caries, though findings were somewhat inconsistent across studies (narrative synthesis; not GRADE-rated).

1 finding from 1 review

ARP with alloplast vs ARP with xenograft

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with alloplast changes implant failure rate compared with ARP with xenograft (very low certainty).

1 finding from 1 review

ARP with allograft (bone graft) vs ARP with xenograft

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Need for additional augmentation prior to implant placement · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

Low birth weight (<2500 g) vs Normal birth weight (2500 g or more)

Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)

Adjusted analyses also showed no association between low birth weight and early childhood caries (adjusted OR 1.05, 95% CI 0.71 to 1.57); certainty not graded.

3 findings from 1 review

Preterm birth (<37 weeks gestation) vs Full-term birth (37 weeks or more gestation)

Early childhood caries (ECC) · Children aged 6 years or younger (preschool children)

In children aged 3 years or younger, preterm birth was not associated with early childhood caries (OR 0.90, 95% CI 0.59 to 1.37); certainty not graded.

2 findings from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Eyes within ± 0.5 D of target refraction · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… showed no clear difference in proportion of eyes within ± 0.5 diopters of target refraction, 12… compared with LASIK with a femtosecond laser (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Mean refractive error expressed as mean spherical equivalent post‐treatment. ‐ 12 months · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism
1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Adverse effects: corneal haze · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… changes corneal haze, any time point compared with LASIK with a femtosecond laser (very low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Dry eye, any time point · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… may leads to higher dry eye, any time point compared with LASIK with a femtosecond laser (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Diffuse lamellar keratitis, any time point · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… may leads to lower diffuse lamellar keratitis, any time point compared with LASIK with a femtosecond laser (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Epithelial ingrowth, any time point · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… changes epithelial ingrowth, any time point compared with LASIK with a femtosecond laser (very low certainty).

1 finding from 1 review

0.1% chlorine dioxide mouthwash vs Placebo mouthwash

Dentist-reported organoleptic test (OLT) score (scale 0 to 5) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

0.1% chlorine dioxide mouthwash may leads to lower dentist-reported organoleptic test (OLT) score (scale 0 to 5) compared with placebo mouthwash (low certainty).

1 finding from 1 review

Mechanical tongue cleaning (tongue scraper) vs No tongue cleaning

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 2 weeks
    Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events.
    0 studies
    No studies found

Lactobacillus salivarius WB21 tablets vs placebo (3 tablets/4 times a day

OLT and VSC scores · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    Suzuki 2014 (cross-over RCT) compared Lactobacillus salivarius WB21 tablets versus placebo tablets (OLT and VSC by gas chromatography). The trial did not give usable data and we could not extract data from the graph.
    1 study
    GRADE not reported

0.6% eucalyptus chewing gum vs 0.4% eucalyptus chewing gum

Dentist-reported organoleptic test (OLT) score (scale 0 to 5) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

It is very uncertain whether 0.6% eucalyptus chewing gum changes dentist-reported organoleptic test (OLT) score (scale 0 to 5) compared with 0.4% eucalyptus chewing gum (very low certainty).

1 finding from 1 review