Healing of MRONJ · People with established (manifest) MRONJ
It is very uncertain whether hyperbaric oxygen therapy (HBO) as an adjunct to conventional therapy changes healing of MRONJ compared with conventional therapy (very low certainty).
1 finding from 1 review
MRONJ (incidence proportion) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ)
It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence proportion) compared with standard care (very low certainty).
1 finding from 1 review
Asthma control · people with asthma
1 finding from 1 review
Asthma exacerbations · people with asthma
Digital adherence interventions may leads to lower asthma exacerbations ‐ Number of people with one or more exacerbations compared with usual care (low certainty).
1 finding from 1 review
Unscheduled healthcare utilisation ‐ number of hospital or GP/ED visits · people with asthma
Digital adherence interventions showed no clear difference in unscheduled healthcare utilisation ‐ number of hospital or GP/ED… compared with usual care (low certainty).
1 finding from 1 review
FEV1 (% predicted): mean change from baseline · people with asthma
1 finding from 1 review
QoL · people with asthma
1 finding from 1 review
Healing of MRONJ (mucosal integrity) · People with MRONJ referred for surgical treatment
It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ (mucosal integrity) compared with tetracycline fluorescence-guided bone surgery (very low certainty).
1 finding from 1 review
Complications and side effects · People on antiresorptive treatment undergoing tooth extraction (at risk of MRONJ)
1 finding from 1 review
No intraoperative complications occurred in either group. Postoperative complications: 6 participants (15.4%) in the mucoperiosteal flap group and 1 participant (2.6%) in the PRF group.
1 study · 77 participants
GRADE not reported
Healing of MRONJ (remission) · People with established (manifest) MRONJ
It is very uncertain whether teriparatide 56.5 microg weekly in addition to standard care changes healing of MRONJ (remission) compared with teriparatide 20 microg daily in addition to standard care (very low certainty).
1 finding from 1 review
MRONJ after tooth extraction (incidence proportion) · People on antiresorptive treatment undergoing tooth extraction (at risk of MRONJ)
Subperiosteal prepared (SPP) wound closure after tooth extraction showed no clear difference in MRONJ after tooth extraction (incidence proportion) compared with epiperiosteal prepared (EPP) wound closure after tooth extraction (low certainty).
1 finding from 1 review
Quality of life · People with established (manifest) MRONJ
1 finding from 1 review
MRONJ (incidence proportion) · People with cancer treated with intravenous bisphosphonates undergoing dental extractions (at risk of MRONJ)
It is very uncertain whether dental extraction protocol with plasma rich in growth factors (PRGF)… changes MRONJ (incidence proportion) compared with standard dental extraction protocol without PRGF (very low certainty).
1 finding from 1 review
MRONJ (incidence rate: cases per patient-year) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ)
It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence rate: cases per patient-year) compared with standard care (very low certainty).
1 finding from 1 review
Seizure freedom · Lennox‐Gastaut syndrome, any age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants with ≥ 75% reduction in all seizures · Lennox‐Gastaut syndrome, any age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
50% or greater reduction in seizure frequency · Lennox‐Gastaut syndrome, any age
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants with adverse events leading to study discontinuation · Lennox‐Gastaut syndrome, any age
Clobazam (low, medium and high doses) plus ASMs leads to higher number of participants with adverse events leading to study… compared with placebo plus ASMs (high certainty).
1 finding from 1 review
Number of participants free from all seizures (recorded by closed‐circuit television and electroencephalography) ‐ · Lennox‐Gastaut syndrome, any age
Felbamate plus ASMs showed no clear difference in number of participants free from all seizures (recorded by… compared with placebo plus ASMs (low certainty).
1 finding from 1 review
Seizure freedom · Lennox‐Gastaut syndrome, any age
1 finding from 1 review