Question · asked by 1 review

Autofluorescence-guided bone surgery vs Tetracycline fluorescence-guided bone surgery: Healing of MRONJ (mucosal integrity)

Population
People with MRONJ referred for surgical treatment
Intervention
Autofluorescence-guided bone surgery
Comparison
Tetracycline fluorescence-guided bone surgery
Outcome
Healing of MRONJ (mucosal integrity)

It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ (mucosal integrity) compared with tetracycline fluorescence-guided bone surgery (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Autofluorescence-guided bone surgery vs Tetracycline fluorescence-guided bone surgery
Healing of MRONJ (mucosal integrity) · People with MRONJ referred for surgical treatment · 1 year
It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ (mucosal integrity) compared with tetracycline fluorescence-guided bone surgery (very low certainty).
Interventions for managing medication‐related osteonecrosis of the jaw (2022) · Cochrane All outcomes
RR 1.05 [0.86, 1.30]1 study · 34 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for managing medication‐related osteonecrosis of the jaw
2022 · Cochrane All outcomes
2021-06Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.