Exacerbations requiring steroids, antibiotics or both · patients with stable chronic obstructive pulmonary disease
It is very uncertain whether aclidinium bromide changes exacerbations requiring steroids, antibiotics or both compared with tiotropium (very low certainty).
1 finding from 1 review
Intervention not reported
Antibiotic use · patients with common cold
The intervention may leads to lower antibiotic use (low certainty).
1 finding from 1 review
Intervention not reported
Serum concentrations ‐ aminoglycoside antibiotics: peak concentration · patients with leading serum concentrations within therapeutic range
1 finding from 1 review
Intervention not reported
Aminoglycoside antibiotics ‐ nephrotoxicity · patients with leading to fewer clinical adverse events
The intervention showed no clear difference in aminoglycoside antibiotics ‐ nephrotoxicity (low certainty).
1 finding from 1 review
Intervention not reported
Length of stay (days) ‐ aminoglycoside antibiotics · saving healthcare resources
1 finding from 1 review
Intervention not reported
Proportion of participants within therapeutic range ‐ aminoglycoside antibiotics: % of participants with peak concentrations adequate after 2 days · patients with leading serum concentrations within therapeutic range
The intervention probably leads to higher proportion of participants within therapeutic range ‐ aminoglycoside… (moderate certainty).
1 finding from 1 review
Moderate exacerbations (course of antibiotics or oral steroids) · patients with chronic obstructive pulmonary disease
Long‐acting beta2‐agonists probably leads to lower moderate exacerbations (course of antibiotics or oral steroids) compared with placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
Antibiotics (i.v.) Rates of patients · breast cancer patients undergoing chemotherapy
The intervention may leads to lower antibiotics (i.v.) Rates of patients (low certainty).
1 finding from 1 review
Intervention not reported
Utilisation of research (Thailand) (for six obstetric practices: social support during labour, magnesium sulphate for eclampsia, corticosteroids to women with preterm birth, selective episiotomy, antibiotic use at caesarean section and vacuum extr... · Healthcare decision makers, health system managers or policy makers
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Intervention not reported
Utilisation of research (Mexico) (for six obstetric practices: social support during labour, magnesium sulphate for eclampsia, corticosteroids to women with preterm birth, selective episiotomy, antibiotic use at caesarean section and vacuum extrac... · Healthcare decision makers, health system managers or policy makers
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Intervention not reported
Utilisation of research (4 obstetric practices: use of polyglycolic acid sutures, ventouse for instrumental delivery, prophylactic antibiotics in caesarean section, and prophylactic corticosteroids in preterm deliveries).2 · Healthcare decision makers, health system managers or policy makers
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Mortality ‐ Antibiotics versus no antibiotics · patients undergoing liver resections
1 finding from 1 review
Mortality ‐ Long duration antibiotics versus short duration antibiotics · patients undergoing liver resections
1 finding from 1 review
Adverse events during treatment · adults and children with cystic fibrosis
The review found no eligible studies for this question.
2 findings from 1 review
Quality of life · adults and children with cystic fibrosis
1 finding from 1 review
Change in sputum P aeruginosa density at end of treatment (cfu/g) · adults and children with cystic fibrosis
Summary of findings: single showed no clear difference in change in sputum P aeruginosa density at end of treatment (cfu/g) compared with combination intravenous anti‐pseudomonal antibiotic therapy (moderate certainty).
2 findings from 1 review
Need for extra treatment · adults and children with cystic fibrosis
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Quality of life  · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
FEV1 % predicted · children with cystic fibrosis
1 finding from 1 review