Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,227 questions · 2,562 findings · 156 reviews · Oral Health

No studies found 297 · 11.6%GRADE not reported 1,616 · 63.1%Very low 405 · 15.8%Low 144 · 5.6%Moderate 81 · 3.2%High 19 · 0.7%

Part-time clear plastic (removable) retainer vs Any type of fixed (bonded) retainer

Adverse effects on oral health: Gingival Index (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether part-time clear plastic (removable) retainer changes adverse effects on oral health: Gingival Index (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Fibre-reinforced composite fixed (bonded) retainer vs Multistrand / spiral wire fixed (bonded) retainer

Adverse effects on oral health: bleeding on probing (lower arch) · People who had received fixed appliance orthodontic treatment

The review found no eligible studies for this question.

1 finding from 1 review

Gum chewing (sugar-free) vs Within-subject before/after comparison of soft gum vs hard gum (no no-gum control)

Oral mucosal moisture · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

One small study found that chewing hard (but not soft) gum increased oral mucosal moisture.

1 finding from 1 review

CAD/CAM nitinol fixed (bonded) retainer vs Multistrand / spiral wire fixed (bonded) retainer

Adverse effects on oral health: Gingival Index (lower arch) · People who had received fixed appliance orthodontic treatment

CAD/CAM nitinol fixed (bonded) retainer showed no clear difference in adverse effects on oral health: Gingival Index (lower arch) compared with conventional/analogue multistrand fixed (bonded) retainer (low certainty).

1 finding from 1 review

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Oral health-related quality of life · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances
1 finding from 1 review

CAD/CAM nitinol fixed (bonded) retainer vs Multistrand / spiral wire fixed (bonded) retainer

Adverse effects on oral health: bleeding on probing (lower arch) · People who had received fixed appliance orthodontic treatment

The review found no eligible studies for this question.

1 finding from 1 review

Malocclusion vs No malocclusion

Poor oral health-related quality of life (OHRQoL) · Adolescents (10-19 years)

Malocclusions probably have a negative effect on OHRQoL in adolescents, after adjustment for confounders (moderate certainty).

1 finding from 1 review

Full-time clear plastic (removable) retainer vs Any type of fixed (bonded) retainer

Adverse effects on oral health: gingival bleeding (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether full-time clear plastic (removable) retainer changes adverse effects on oral health: gingival bleeding (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Fibre-reinforced composite fixed (bonded) retainer vs Multistrand / spiral wire fixed (bonded) retainer

Adverse effects on oral health: Gingival Index (lower arch) · People who had received fixed appliance orthodontic treatment

The review found no eligible studies for this question.

1 finding from 1 review

Full-time clear plastic (removable) retainer vs Any type of fixed (bonded) retainer

Adverse effects on oral health: caries (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether full-time clear plastic (removable) retainer changes adverse effects on oral health: caries (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Chlorhexidine vs Essential oils/herbal mouthwash

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them

Chlorhexidine (CHX) led to lower reduction in level of contamination by particles >5 um (droplets) at… compared with essential oils/herbal mouthwash; GRADE not reported.

4 findings from 1 review
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Essential oil mouthwash vs Coloured and flavoured 5% hydroalcohol mouthwash

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
1 finding from 1 review

Povidone iodine vs Ozonated water

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them

It is very uncertain whether povidone iodine changes reduction in level of contamination by particles >5 um (droplets) at… compared with ozonated water (very low certainty).

1 finding from 1 review

Machine-learning algorithms for dental caries detection vs Different machine-learning algorithms for caries prediction

Caries detection accuracy on intraoral images · Dental images of human beings

The review reported 93.3% accuracy for caries detection on intraoral images in Kühnisch et al. (Ungraded).

1 finding from 1 review

Chlorhexidine vs Cetylpyridinium chloride (CPC)

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them

It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty).

9 findings from 1 review
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Chlorhexidine vs Water (distilled)

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
5 findings from 1 review
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Cetylpyridinium chloride (CPC) vs No rinsing

Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them

It is very uncertain whether cetylpyridinium chloride (CPC) changes reduction in level of contamination by particles >5 um (droplets) at… compared with no rinsing (very low certainty).

3 findings from 1 review

Chlorhexidine vs povidone‐iodine

Reduction in level of contamination by particles <=5 um (droplet nuclei) at >=2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them

It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles <=5 um (droplet… compared with povidone iodine (very low certainty).

2 findings from 1 review