Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,410 questions · 8,901 findings · 1,091 reviews

No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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CBT vs TAU

AEs · chronic pain (excluding headache) in adults
2 findings from 1 review · compare the 2 reviews

Brexpiprazole vs antidepressive agents

Adverse effects: 2. Extrapyramidal ‐ akathisia · participants of any age with a primary diagnosis of major depressive disorder

Brexpiprazole probably leads to higher adverse effects: akathisia (followed up until the end of the longest compared with antidepressive agents (moderate certainty).

1 finding from 1 review

Brexpiprazole vs antidepressive agents

Weight gain · participants of any age with a primary diagnosis of major depressive disorder

Brexpiprazole probably leads to higher adverse effects: weight gain (followed up until the end of the longest compared with antidepressive agents (moderate certainty).

1 finding from 1 review

Hypothermic oxygenated perfusion (HOPE) vs static cold storage (SCS)

Ischaemic biliary complications (donated following brain death (DBD)) · liver transplant recipients

Hypothermic oxygenated perfusion (HOPE) showed no clear difference in ischaemic biliary complications (donated following brain death (DBD)) compared with static cold storage (SCS); GRADE not reported.

1 finding from 1 review

Hypothermic oxygenated perfusion (HOPE) vs static cold storage (SCS)

Ischaemic biliary complications (donated following circulatory death (DCD)) · liver transplant recipients

Hypothermic oxygenated perfusion (HOPE) led to lower ischaemic biliary complications (donated following circulatory death… compared with static cold storage (SCS); GRADE not reported.

1 finding from 1 review