Dental caries prevalence · Brazilian children/adolescents in permanent dentition (BMI classified by CDC 2000 growth charts)
Overweight may make little or no difference to the odds of caries in the permanent dentition (very low certainty).
1 finding from 1 review
Determinants of oral diseases · Adult residents of slums and non-slum urban settings of LMICs
Age, education, income, oral-hygiene behaviour, dental-visit pattern and slum/disadvantaged residence are associated with oral disease; gender effects are disease-specific; ungraded.
1 finding from 1 review
Fourteen studies reported determinants: older age, less education, lower income, poor oral hygiene behaviour (brushing frequency, technique), infrequent dental visits and disadvantaged/slum residential setting were…
14 studies
GRADE not reported
Intra-examiner reliability · Children and adults with primary or permanent dentition
Intra-examiner kappa statistics ranged from 0.52 to 1.00 across 6 studies; no meta-analysis or GRADE rating was reported.
1 finding from 1 review
no estimate extracted
6 studies
GRADE not reported
Cell damage or cytotoxicity · Streptococcus mutans (in vitro cultures and biofilms)
No meta-analysis was conducted; one included study reported very low cell damage with grape seed extract.
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Inter-examiner reliability · Children and adults with primary or permanent dentition undergoing dental caries assessment
Inter-examiner reliability ranged from kappa 0.44 to 0.91 across 13 studies (moderate to almost perfect agreement); certainty not graded.
1 finding from 1 review
Change in Mutans streptococci (MS) count in dental plaque · healthy people
Xylitol reduced Mutans streptococci in dental plaque more than sorbitol (SMD -0.45, 95% CI -0.69 to -0.21; 4 trials, I2=7%); not GRADE-rated.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
MTA and Biodentine have similar pulpotomy success (OR 0.89, not significant; low certainty).
1 finding from 1 review
White spot lesion formation (QLF: fluorescence loss, lesion area) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)
Indirect bonding with a flowable adhesive favored less QLF-measured demineralization, with certainty not graded.
1 finding from 1 review
The DB group exhibited significantly higher loss of fluorescence and degree of demineralization compared to the IB group between T0 and T1, with notable differences in specific quadrants (p <0.05 for ΔF and ΔF max).
1 study · 51 participants
GRADE not reported
Dental caries · Children (<18 years) with vs without dental caries
TaqI/BglI(rs739837) over-dominant model: TT+GG vs TG was not significantly associated with dental caries (OR 0.89); ungraded.
1 finding from 1 review
Antioxidant capacity · Streptococcus mutans (in vitro cultures and biofilms)
One study reported antioxidant activity of cranberry polyphenol fractions (ungraded).
1 finding from 1 review
Caries arrestment at the surface level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
SDF probably makes little to no difference to surface-level caries arrestment versus other methods (moderate certainty).
1 finding from 1 review
Dental caries susceptibility · Institutionalized orphan children (roughly 3 to 18 years)
Primary teeth may carry a higher caries risk than permanent teeth in institutionalized children (RR 1.31), but the difference is not statistically significant (very low certainty).
1 finding from 1 review
Dental caries prevalence · Brazilian children under 5 years in primary dentition (BMI classified by WHO 2006 Z-score)
The evidence is very uncertain about the effect of overweight/obesity on caries odds in the primary dentition (WHO 2006 Z-score; very low certainty).
1 finding from 1 review
OR 0.86 [0.60, 1.22]
3 studies
Very low
Dental caries - SNP-based heritability · Japanese adults (present-study cohort)
SNP-based heritability of dental caries was low (h2=0.0258, SE 0.0155); ungraded.
1 finding from 1 review
Intervention not reported
Overall success (composite of clinical and radiographic success)
1 finding from 1 review
Caries arrestment at the tooth level · Children and adults without systemic diseases affecting dental health
SDF showed a higher caries-free proportion at the tooth level, but the reported difference was not statistically significant.
1 finding from 1 review
Dental caries · Children (<18 years) with vs without dental caries
Recessive model (CC vs CT+TT) at FokI(rs10735810) showed no significant association with caries (OR 1.23, 95% CI 0.97-1.55); ungraded.
1 finding from 1 review
Dental caries prevalence · Brazilian children in primary dentition (BMI classified by CDC 2000 growth charts)
The evidence is very uncertain about the effect of obesity on caries odds in the primary dentition (very low certainty).
1 finding from 1 review
Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)
In the mandible, extraction before age 8 (vs after 10) increases odds of space closure (OR 5.01; low certainty).
1 finding from 1 review
GtfB/C and F-ATPase activity · Streptococcus mutans (in vitro cultures and biofilms)
Cranberry proanthocyanidins downregulate GtfB/C and F-ATPase activity of S. mutans (5 studies; ungraded).
1 finding from 1 review