Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,429 questions · 3,558 findings · 436 reviews

No studies found 660 · 18.5%GRADE not reported 375 · 10.5%Very low 727 · 20.4%Low 887 · 24.9%Moderate 709 · 19.9%High 200 · 5.6%

Alternative lipid emulsion (LE) vs S‐LE

Bronchopulmonary dysplasia/chronic lung disease · Parenterally fed preterm infants

It is very uncertain whether all alternative LE changes bronchopulmonary dysplasia/chronic lung disease compared with S‐LE (very low certainty).

1 finding from 1 review · compare the 2 reviews

Intervention not reported

Maximal exercise capacity (Change in peak work rate) Cardiopulmonary exercise test · people with dust‐related respiratory diseases

It is very uncertain whether the intervention changes maximal exercise capacity (Change in peak work rate) Cardiopulmonary… (very low certainty).

1 finding from 1 review

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Pulmonary hemorrhage · Preterm infants for treatment of RDS

Bovine lung lavage surfactant extract showed no clear difference in pulmonary hemorrhage compared with modified bovine minced lung surfactant extract (moderate certainty).

1 finding from 1 review

Modified bovine minced lung surfactant extract vs porcine minced lung surfactant extract

Pulmonary hemorrhage · Preterm infants for treatment of RDS

Modified bovine minced lung surfactant extract showed no clear difference in pulmonary hemorrhage compared with porcine minced lung surfactant extract (low certainty).

1 finding from 1 review

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Pulmonary hemorrhage · Preterm infants for prevention of RDS

Bovine lung lavage surfactant extract showed no clear difference in pulmonary hemorrhage compared with modified bovine minced lung surfactant extract (low certainty).

1 finding from 1 review

Intervention not reported

Impulse control disorders (adverse effect, post‐intervention) · people with Parkinson's disease

The intervention showed no clear difference in impulse control disorders (adverse effect, post‐intervention) (moderate certainty).

1 finding from 1 review

Intervention not reported

Impulse control disorders (adverse effect, post‐intervention) · people with Parkinson's disease

The intervention showed no clear difference in impulse control disorders (adverse effect, post‐intervention) (moderate certainty).

1 finding from 1 review

Intervention not reported

Incidence of pulmonary tuberculosis in children with HIV infection ‐ isoniazid prophylaxis only · children with HIV infection aged 12 years and under

The intervention showed no clear difference in incidence of pulmonary tuberculosis in children with HIV infection ‐… (moderate certainty).

1 finding from 1 review

Repair of a defective resin composite restoration in a permanent molar or premolar tooth (with resin composite) vs Replacement of a defective resin composite restoration in a permanent molar or premolar tooth (with resin composite)

Presence of clinical symptoms (pain, swelling, diagnosis of pulpitis, abscess formation) · Adults (16 years or over) with one or more defective resin composite restoration(s) in a molar or premolar tooth/teeth

The review found no eligible studies for this question.

1 finding from 1 review

TCu 220C vs Copper 7

Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to expulsion (750 days) compared with copper 7 (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion

TCu 220C probably leads to lower discontinuation rate due to expulsion (750 days) Tietze‐Potter gross… compared with lippes Loop (moderate certainty).

1 finding from 1 review

Intervention not reported

Positive xenodiagnosis: all populations ‐ RCT data ‐ nitroderivatives Xenodiagnosis · people with chronic asymptomatic Trypanosoma cruzi infection

The intervention leads to lower positive xenodiagnosis: all populations ‐ RCT data ‐… (high certainty).

1 finding from 1 review