Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,511 questions · 2,668 findings · 290 reviews

No studies found 743 · 27.8%GRADE not reported 329 · 12.3%Very low 775 · 29%Low 484 · 18.1%Moderate 279 · 10.5%High 58 · 2.2%

Endovascular coiling vs neurosurgical clipping

Delayed cerebral ischaemia · people with subarachnoid haemorrhage from a ruptured intracranial aneurysm

Endovascular coiling probably leads to lower delayed cerebral ischaemia (2–3 months) compared with neurosurgical clipping (moderate certainty).

1 finding from 1 review

Endovascular coiling vs neurosurgical clipping

Rebleeding · people with subarachnoid haemorrhage from a ruptured intracranial aneurysm

Endovascular coiling leads to higher rebleeding postprocedure up to 1 year compared with neurosurgical clipping (high certainty).

2 findings from 1 review

Endovascular coiling vs neurosurgical clipping

Complications from the intervention · people with subarachnoid haemorrhage from a ruptured intracranial aneurysm

Endovascular coiling showed no clear difference in complications from the intervention compared with neurosurgical clipping (low certainty).

1 finding from 1 review

Intervention not reported

Postoperative delirium (POD) within 7 days (As assessed by any method such as the Mini‐Mental State Examination (MMSE) and Confusion Assessment Method (CAM) in the first week after operation) · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations

The intervention probably leads to lower postoperative delirium (POD) within 7 days (As assessed by any… (moderate certainty).

1 finding from 1 review

Intervention not reported

Postoperative cognitive dysfunction (POCD) (As determined by any method of assessing POCD including a battery of neuropsychological tests according to the criteria described by the International Study of Postoperative Cognitive Dysfunction (ISPOCD)) · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations

The intervention showed no clear difference in postoperative cognitive dysfunction (POCD) (As determined by any… (moderate certainty).

1 finding from 1 review

Intervention not reported

Any postoperative complication · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations

The intervention probably leads to lower any postoperative complication (moderate certainty).

1 finding from 1 review

Intervention not reported

Discharge to an increased level of care · Improving outcomes in older adult people admitted to a surgical service.

The intervention leads to lower discharge to an increased level of care (high certainty).

1 finding from 1 review

Duodenal stenting vs surgical palliation

Re‐establishment of oral intake (technical success of the intervention) · people with malignant gastric outlet obstruction

Duodenal stenting showed no clear difference in re‐establishment of oral intake (technical success of the… compared with surgical palliation (low certainty).

1 finding from 1 review