Cochrane · systematic review · CD003085

Endovascular coiling versus neurosurgical clipping for people with aneurysmal subarachnoid haemorrhage

Lindgren, A, Vergouwen, MDI, van der Schaaf, I, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 3 · 42.9%High 1 · 14.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Endovascular coiling compared with neurosurgical clipping for subarachnoid haemorrhage

Population: people with subarachnoid haemorrhage from a ruptured intracranial aneurysm
7 questions
OutcomeEffectEvidenceStatus / GRADE
Poor outcome: death or dependence in daily activities (12 months)
Endovascular coiling vs neurosurgical clipping
RR 0.77 [0.67, 0.87]4 studies · 2429 participantsModerate
Downgraded: indirectness
Poor outcome (death or dependence) (10 years)
Endovascular coiling vs neurosurgical clipping
RR 0.81 [0.7, 0.92]1 study · 1316 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Death from any cause (12 months)
Endovascular coiling vs neurosurgical clipping
RR 0.8 [0.63, 1.02]4 studies · 2429 participantsModerate
Downgraded: indirectness
Delayed cerebral ischaemia (2–3 months)
Endovascular coiling vs neurosurgical clipping
RR 0.84 [0.74, 0.96]4 studies · 2450 participantsModerate
Downgraded: indirectness
Rebleeding postprocedure up to 1 year
Endovascular coiling vs neurosurgical clipping
RR 1.83 [1.04, 3.23]4 studies · 2458 participantsHigh
Rebleeding postprocedure up to 10 years
Endovascular coiling vs neurosurgical clipping
RR 2.69 [1.5, 4.81]1 study · 1323 participantsLow
Downgraded: risk of bias, imprecision, indirectness
Complications from the intervention
Endovascular coiling vs neurosurgical clipping
RR 1.05 [0.44, 2.53]2 studies · 129 participantsLow
Downgraded: risk of bias, imprecision, indirectness