Findings

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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Chemotherapy regimen A (+/- locoregional treatment) vs Chemotherapy regimen B (+/- locoregional treatment)

Overall survival (total mortality), chemotherapy regimen A vs regimen B · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer
1 finding from 1 review

Electrical conductance devices (electronic caries monitor (ECM) and/or CarieScan Pro), used as an adjunct to clinical oral examination vs Reference standard: histology or enhanced visual examination (with or without radiographs)

Outcome not reported · Children/adolescents/adults or extracted teeth; target condition = non-cavitated enamel caries on SMOOTH tooth surfaces.

The review found no eligible studies for this question.

1 finding from 1 review
  • Electrical conductance for the detection of dental caries 2021 · Cochrane All outcomes
    Up to 3 months between index test and reference standard (in vivo studies)
    No eligible studies. All included studies assessed occlusal surfaces only; smooth surfaces were a planned surface subgroup with no data.
    0 studies
    No studies found

Extraction of the primary (baby) canine (single primary tooth extraction) vs No extraction (non-intervention control)

Effect of severity of PDC displacement towards the midline on the proportion of successful eruptions · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)
1 finding from 1 review

Non-selective carious tissue removal and conventional restoration (CR) vs Hall Technique (sealing with a preformed metal crown)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

Non-selective carious tissue removal and conventional restoration (CR) may leads to higher failure of therapy compared with hall Technique (sealing with a preformed metal crown) (low certainty).

1 finding from 1 review

Vibrational appliance with fixed appliances vs Fixed appliances

Amount of crowding · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether vibrational appliance with fixed appliances changes amount of crowding (change in mandibular crowding) at 10 to 30 weeks compared with fixed appliances only / no vibrational appliance (control) (very low certainty).

1 finding from 1 review

In-office laser therapy (all types combined) vs Placebo (placebo laser or placebo agent) or no treatment

Adverse events · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation
2 findings from 1 review

ARP with allograft (bone graft) vs ARP with xenograft

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with allograft changes changes in vertical height of alveolar ridge (mm) compared with ARP with xenograft (very low certainty).

1 finding from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Adverse events (participants with adverse events or withdrawals due to adverse events) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
1 finding from 1 review

Electrical conductance devices (electronic caries monitor (ECM) and/or CarieScan Pro), used as an adjunct to clinical oral examination vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity · Children, adolescents, or adults presenting asymptomatically or suspected of early enamel caries (in vivo), or extracted teeth of…
2 findings from 1 review

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Systolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in change in systolic blood pressure (SBP, mmHg) compared with no treatment (no periodontal treatment) (low certainty).

4 findings from 1 review
Show 1 more finding
  • Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
    Short term (follow-up 3 months) · People diagnosed with periodontitis and other cardiovascular diseases except hypertension
    MD 0.59 [-9.18, 10.36]
    1 study · 55 participants
    Very low

Bone-borne expansion vs Fixed tooth-borne expansion (Hyrax)

Crossbite correction · Children and adults with a posterior crossbite, without a Class III skeletal relationship, cleft lip or palate (or both), or other…

Bone-borne expansion showed no clear difference in crossbite correction compared with fixed tooth-borne expansion (Hyrax) (low certainty).

1 finding from 1 review

Direct composite resin restoration vs Amalgam restoration

Secondary caries · People with permanent or adult posterior teeth requiring restoration (parallel-group trials involved children aged 6 to 12 years)

Direct composite resin restoration showed no clear difference in secondary caries compared with amalgam restoration; GRADE not reported.

3 findings from 1 review

Chemotherapy vs Placebo

Outcome not reported · People receiving curative-intent treatment for oral cavity and oropharyngeal (squamous cell) cancer

The review found no eligible studies for this question.

1 finding from 1 review

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

Incidence of successfully erupted PDC that were favourably positioned · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

Double primary (canine and first molar) tooth extraction showed no clear difference in incidence of successfully erupted PDC that were favourably positioned compared with single primary (canine) tooth extraction; GRADE not reported.

3 findings from 1 review

Lower lip bumper vs No active treatment (control)

Lower incisors to mandible (position, mm) at 9 months · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Lower lip bumper led to higher lower incisors to mandible at 6 months compared with no active treatment (control); GRADE not reported.

1 finding from 1 review

Electrical conductance devices (electronic caries monitor (ECM) and/or CarieScan Pro), used as an adjunct to clinical oral examination vs Reference standard (histology, excavation, or enhanced visual examination)

Sensitivity for detection of enamel caries · Children, adolescents, or adults presenting asymptomatically or suspected of early enamel caries (in vivo), or extracted teeth of…
1 finding from 1 review
  • Electrical conductance for the detection of dental caries 2021 · Cochrane All outcomes
    Up to 3 months between index test and reference standard (in vivo studies)
    SoF findings (HSROC; no summary operating point reported): 'ECM: sensitivity from 0.61 to 0.98 ... CarieScan Pro: sensitivity from 0.55 to 0.91'. Across all 7 studies (8 datasets), covering 719 tooth surfaces or sites…
    7 studies
    Very low

Nickel-titanium archwire vs Stainless steel archwire

Amount of crowding (change in mandibular crowding) at 8 weeks · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

It is very uncertain whether nickel-titanium archwire changes amount of crowding (change in mandibular crowding) at 8 weeks compared with stainless steel archwire (very low certainty).

1 finding from 1 review

Cervical pull headgear vs Minor interceptive procedures (control)

Size of the jaws (maxillary and mandibular arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Cervical pull headgear led to higher size of the jaws (maxillary and mandibular arch length) compared with minor interceptive procedures (control); GRADE not reported.

1 finding from 1 review