Hypertonic salt vs isotonic salt solution
Maximum intraoperative cardiac index · any people undergoing surgery with fluid resuscitation
1 finding from 1 review
- no estimate extracted6 studies · 418 participantsHigh
Findings
What do systematic reviews say?
884 questions · 892 findings · 68 reviews · Anaesthesia
No studies found 118 · 13.2%GRADE not reported 156 · 17.5%Very low 187 · 21%Low 270 · 30.3%Moderate 119 · 13.3%High 42 · 4.7%
Active body surface warming systems vs control
Infection and complications of the surgical wound · adults undergoing surgery
Active body surface warming systems may leads to lower infection and complications of the surgical wound compared with control (low certainty).
1 finding from 1 review
- Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in… 2016 · Cochrane Headline outcomes onlyRR 0.36 [0.2, 0.66]3 studies · 589 participantsLow
Active body surface warming systems vs control
Major cardiovascular complications (cardiovascular death, non‐fatal myocardial infarction, non‐fatal stroke, and non‐fatal cardiac arrest) · adults undergoing surgery
Active body surface warming systems showed no clear difference in major cardiovascular complications (cardiovascular death, non‐fatal… compared with control (low certainty).
1 finding from 1 review
- Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in… 2016 · Cochrane Headline outcomes onlyRR 0.22 [0.05, 1]1 study · 300 participantsLow
Active body surface warming systems vs control
All‐cause mortality · adults undergoing surgery
Active body surface warming systems showed no clear difference in all‐cause mortality compared with control (low certainty).
1 finding from 1 review
- Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in… 2016 · Cochrane Headline outcomes onlyRR 1.01 [0.26, 4]2 studies · 500 participantsLow
Active body surface warming systems vs control
Number of patients transfused ( · adults undergoing surgery
Active body surface warming systems showed no clear difference in participants transfused compared with control (moderate certainty).
1 finding from 1 review
- Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in… 2016 · Cochrane Headline outcomes onlyRR 0.79 [0.5, 1.23]8 studies · 621 participantsModerate
Active body surface warming systems vs control
Shivering · adults undergoing surgery
Active body surface warming systems leads to lower chills/shivering compared with control (high certainty).
1 finding from 1 review
- Active body surface warming systems for preventing complications caused by inadvertent perioperative hypothermia in… 2016 · Cochrane Headline outcomes onlyRR 029 studies · 1922 participantsHigh
CHRONIC: ACEi or ARB vs placebo
All‐cause mortality · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively
It is very uncertain whether ACEIs or ARBs changes all‐cause mortality compared with placebo (very low certainty).
1 finding from 1 review
- Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes onlyRR 1.61 [0.44, 5.85]3 studies · 419 participantsVery low
CHRONIC: ACEi or ARB vs placebo
Risk of acute myocardial ischaemia · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively
It is very uncertain whether ACEIs or ARBs changes risk of acute myocardial ischaemia compared with placebo (very low certainty).
1 finding from 1 review
- Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes onlyRR 0.55 [0.14, 2.26]2 studies · 345 participantsVery low
CHRONIC: ACEi or ARB vs placebo
Congestive heart failure · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively
1 finding from 1 review
- Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 34 participantsVery low
CHRONIC: ACEi or ARB vs placebo
Hypotension · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively
It is very uncertain whether ACEIs or ARBs changes hypotension compared with placebo (very low certainty).
1 finding from 1 review
- Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes onlyRR 1.95 [0.86, 4.41]1 study · 298 participantsVery low
CHRONIC: ACEi or ARB vs placebo
Rate of perioperative cerebrovascular complications · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively
It is very uncertain whether ACEIs or ARBs changes rate of perioperative cerebrovascular complications compared with placebo (very low certainty).
1 finding from 1 review
- Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes onlyRR 0.48 [0.18, 1.28]3 studies · 459 participantsVery low
CHRONIC: ACEi or ARB vs placebo
Length of hospital stay · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively
1 finding from 1 review
- Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 372 participantsVery low
CHRONIC: ACEi or ARB vs placebo
Treatment related adverse events · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively
1 finding from 1 review
- Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing… 2016 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 385 participantsVery low
Intervention not reported
Risk of hypothermia ‐ not reported · adults undergoing surgery.
The review found no eligible studies for this question.
1 finding from 1 review
- Intravenous nutrients for preventing inadvertent perioperative hypothermia in adults 2016 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Intervention not reported
Mean core temperature, 60 minutes · adults undergoing surgery.
1 finding from 1 review
- Intravenous nutrients for preventing inadvertent perioperative hypothermia in adults 2016 · Cochrane Headline outcomes onlyno estimate extracted9 studies · 363 participantsVery low
Intervention not reported
Mean core temperature, 120 minutes · adults undergoing surgery.
1 finding from 1 review
- Intravenous nutrients for preventing inadvertent perioperative hypothermia in adults 2016 · Cochrane Headline outcomes onlyno estimate extracted10 studies · 347 participantsVery low
Intervention not reported
Shivering · adults undergoing surgery.
It is very uncertain whether the intervention changes shivering (very low certainty).
1 finding from 1 review
- Intravenous nutrients for preventing inadvertent perioperative hypothermia in adults 2016 · Cochrane Headline outcomes onlyRR 0.36 [0.13, 1]3 studies · 155 participantsVery low
Intervention not reported
Major cardiovascular event ‐ not reported · adults undergoing surgery.
The review found no eligible studies for this question.
1 finding from 1 review
- Intravenous nutrients for preventing inadvertent perioperative hypothermia in adults 2016 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Intervention not reported
Mortality within the longest · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
The intervention showed no clear difference in mortality within the longest (low certainty).
1 finding from 1 review
- The effects of high perioperative inspiratory oxygen fraction for adult surgical patients 2015 · Cochrane Headline outcomes onlyRR 1.12 [0.93, 1.36]3 studies · 4758 participantsLow
Intervention not reported
Mortality within the longest · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
It is very uncertain whether the intervention changes mortality within the longest (very low certainty).
1 finding from 1 review
- The effects of high perioperative inspiratory oxygen fraction for adult surgical patients 2015 · Cochrane Headline outcomes onlyRR 1.07 [0.87, 1.33]6 studies · 4525 participantsVery low