CHRONIC: ACEi or ARB vs placebo: Risk of acute myocardial ischaemia
It is very uncertain whether ACEIs or ARBs changes risk of acute myocardial ischaemia compared with placebo (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
ACEIs or ARBs vs placebo Risk of acute myocardial ischaemia · Patients undergoing any type of surgery under general anaesthesia receiving ACEIs or ARBs perioperatively It is very uncertain whether ACEIs or ARBs changes risk of acute myocardial ischaemia compared with placebo (very low certainty). Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for… (2016) · Cochrane Headline outcomes only | RR 0.55 [0.14, 2.26] | 2 studies · 345 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing mortality and morbidity… 2016 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.