Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,247 questions · 1,321 findings · 334 reviews

No studies found 73 · 5.5%GRADE not reported 31 · 2.3%Very low 500 · 37.9%Low 406 · 30.7%Moderate 247 · 18.7%High 64 · 4.8%

Local corticosteroid injection (LCI) vs a control strategy (no treatment, placebo or waiting list controls)

Heel pain: VAS 0 to 100 (higher scores = worse pain) ‐ short‐term · Adults with plantar heel pain¹

Local steroid injection showed no clear difference in heel pain: VAS 0 to 100 (higher scores = worse pain) ‐ short‐term compared with placebo or no treatment control (low certainty).

1 finding from 1 review

Local corticosteroid injection (LCI) vs a control strategy (no treatment, placebo or waiting list controls)

Heel pain: VAS 0 to 100 (higher scores = worse pain) ‐ medium‐term · Adults with plantar heel pain¹

Local steroid injection showed no clear difference in heel pain: VAS 0 to 100 (higher scores = worse pain) ‐ medium‐term compared with placebo or no treatment control (low certainty).

1 finding from 1 review

Local corticosteroid injection (LCI) vs a control strategy (no treatment, placebo or waiting list controls)

Function: medium‐term FFI (0 to 100: higher scores = worse function) FHSQ (0 to 100: higher scores = better function · Adults with plantar heel pain¹

It is very uncertain whether local steroid injection changes function: medium‐term FFI (0 to 100: higher scores = worse function)… compared with placebo or no treatment control (very low certainty).

1 finding from 1 review

Intervention not reported

Severity of ADHD (at study completion) WRAADDS scale (0 to 28), ADHD‐RS scale (0 to 54) or CAARS scale (0 to 48). On all scales, a higher score equates to more symptoms (at 6 weeks) · Adults with ADHD
1 finding from 1 review

Zonisamide vs placebo

Functional abilities Change in TRS part B score (motor tasks) Change in TRS part C score (functional disability) (higher scores indicate a better outcome) · patients with essential tremor

It is very uncertain whether zonisamide changes functional abilities Change in TRS part B score (motor tasks) Change… compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Health‐related quality of life (HRQOL), SD units: measured on FACIT‐Pal, TOI of FACT‐Hep, TOI of FACT‐L, FACT‐G, McGill Quality of Life, FACIT‐Sp. Higher scores indicate better HRQOL. · patients with advanced cancer
1 finding from 1 review

Intervention not reported

Depression, SD units: measured on CES‐D, HADS‐D, PHQ‐9. Higher scores indicate higher depressive symptom load. · patients with advanced cancer
1 finding from 1 review

Intervention not reported

Depression, natural units: measured on CES‐D (from 0 to 60). Higher scores indicate higher depressive symptom load · patients with advanced cancer
1 finding from 1 review