Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

Methylphenidate vs placebo or no intervention

ADHD symptoms · Children and adolescents with ADHD

It is very uncertain whether methylphenidate changes ADHD symptoms: all parallel‐group trials and first‐period cross‐over… compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Short‐term mortality (30‐day or in‐hospital) · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in short‐term mortality (30‐day or in‐hospital) compared with cut‐down femoral artery access (low certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Wound infection · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in wound infection (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Major complications · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in major complications (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Bleeding complications (30‐day or in‐hospital) · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in bleeding complications (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review