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What do systematic reviews say?

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Evidence found and GRADE certainty

461 questions · 473 findings · 36 reviews · HIV/AIDS

No studies found 38 · 8%GRADE not reported 9 · 1.9%Very low 126 · 26.6%Low 127 · 26.8%Moderate 152 · 32.1%High 21 · 4.4%

Vincristine + ART vs Bleomycin + vincristine + ART

Complete/Partial: Vincristine+ART vs Bleomycin+vincristine+ART · Kaposi sarcoma in children with HIV‐1 infection

It is very uncertain whether vincristine + ART changes complete/Partial: Vincristine+ART vs Bleomycin+vincristine+ART compared with bleomycin + vincristine + ART (very low certainty).

1 finding from 1 review

ART alone vs Vincristine or Bleomycin

Brain tumour response rates: complete response (CR) and partial response (PR) combinedNo. of participants: 847(6 RCTs) · Kaposi sarcoma in children with HIV‐1 infection

It is very uncertain whether ART alone changes complete or Partial Response compared with vincristine or Bleomycin (very low certainty).

1 finding from 1 review