Question · asked by 1 review
ART alone vs Vincristine or Bleomycin: Brain tumour response rates: complete response (CR) and partial response (PR) combinedNo. of participants: 847(6 RCTs)
- Population
- Kaposi sarcoma in children with HIV‐1 infection
- Intervention
- ART alone
- Comparison
- Vincristine or Bleomycin
- Outcome
- Brain tumour response rates: complete response (CR) and partial response (PR) combinedNo. of participants: 847(6 RCTs)
It is very uncertain whether ART alone changes complete or Partial Response compared with vincristine or Bleomycin (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
ART alone vs Vincristine or Bleomycin Complete or Partial Response · Kaposi sarcoma in children with HIV‐1 infection It is very uncertain whether ART alone changes complete or Partial Response compared with vincristine or Bleomycin (very low certainty). Treatment of Kaposi sarcoma in children with HIV‐1 infection (2014) · Cochrane Headline outcomes only | RR 0.2 [0.05, 0.79] | 24 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Treatment of Kaposi sarcoma in children with HIV‐1 infection 2014 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.