Question · asked by 1 review
Vincristine + ART vs Bleomycin + vincristine + ART: Complete: Vincristine+ART vs Bleomycin+vincristine+ART
- Population
- Kaposi sarcoma in children with HIV‐1 infection
- Intervention
- Vincristine + ART
- Comparison
- Bleomycin + vincristine + ART
- Outcome
- Complete: Vincristine+ART vs Bleomycin+vincristine+ART
It is very uncertain whether vincristine + ART changes complete: Vincristine+ART vs Bleomycin+vincristine+ART compared with bleomycin + vincristine + ART (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Vincristine + ART vs Bleomycin + vincristine + ART Complete: Vincristine+ART vs Bleomycin+vincristine+ART · Kaposi sarcoma in children with HIV‐1 infection It is very uncertain whether vincristine + ART changes complete: Vincristine+ART vs Bleomycin+vincristine+ART compared with bleomycin + vincristine + ART (very low certainty). Treatment of Kaposi sarcoma in children with HIV‐1 infection (2014) · Cochrane Headline outcomes only | RR 0.69 [0.33, 1.47] | 26 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Treatment of Kaposi sarcoma in children with HIV‐1 infection 2014 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.