Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

884 questions · 892 findings · 68 reviews · Anaesthesia

No studies found 118 · 13.2%GRADE not reported 156 · 17.5%Very low 187 · 21%Low 270 · 30.3%Moderate 119 · 13.3%High 42 · 4.7%

Intervention not reported

Adverse events (Re‐operation for bleeding (reoperation for major bleeding within 30 days (yes/no))) · adults undergoing surgery

It is very uncertain whether the intervention changes adverse events (Re‐operation for bleeding (reoperation for major… (very low certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Intraoperative pain or discomfort (dichotomous data) · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine probably leads to lower intraoperative pain or discomfort (dichotomous data) compared with topical anaesthesia alone (moderate certainty).

1 finding from 1 review

Topical anaesthesia plus intracameral lidocaine vs topical anaesthesia alone

Intraoperative adverse surgical events attributable to choice of anaesthesia · adults undergoing phacoemulsification cataract surgery

Topical anaesthesia plus intracameral lidocaine showed no clear difference in intraoperative adverse surgical events attributable to choice of… compared with topical anaesthesia alone (low certainty).

1 finding from 1 review

rHuEPO with iron vs control treatment with or without iron

Blood transfusion · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia

rHuEPO with iron probably leads to lower transfusion (measured in participants during or up to 5 days after… compared with control treatment with or without iron (moderate certainty).

1 finding from 1 review

rHuEPO with iron vs control treatment with or without iron

Number of RBC units transfused per participant (intraoperative to 5 days postoperative) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia
1 finding from 1 review

rHuEPO with iron vs control treatment with or without iron

Adverse events (number of participants with any adverse event) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia

rHuEPO with iron showed no clear difference in adverse events (number of participants with any adverse event) compared with control treatment with or without iron (moderate certainty).

1 finding from 1 review