Findings

What do systematic reviews say?

83 questions · 83 findings · 9 reviews

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No studies found 34 · 41%GRADE not reported 1 · 1.2%Very low 24 · 28.9%Low 13 · 15.7%Moderate 11 · 13.3%High 0 · 0%

Lateral vs supine

Oxygenation SpO21 · neonates with mechanical ventilation

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 206 participants
Very low

Lateral vs supine

Episodes of oxygen desaturation · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prone vs supine

Long‐term complications (bronchopulmonary dysplasia, chronic lung disease) · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prone vs supine

Short‐term complications (respiratory) · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prone vs supine

Short‐term complications (procedural) · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prone vs supine

Periventricular or intraventricular haemorrhage · neonates with mechanical ventilation

The review found no eligible studies for this question.

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prone vs supine

Oxygenation: PO2 (mmHg)a · neonates with mechanical ventilation

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 116 participants
Moderate

Prone vs supine

Oxygenation: SpO2e · neonates with mechanical ventilation

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 308 participants
Very low

Prone vs supine

SpO2 at ‐ sensitivity low risk; selection bias · neonates with mechanical ventilation

1 finding from 1 review

Infant position in neonates receiving mechanical ventilation 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 92 participants
Moderate

Lateral positioning vs supine immobilization

Mortality ‐ not measured · critically ill adult patients

The review found no eligible studies for this question.

1 finding from 1 review

Lateral positioning for critically ill adult patients 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Lateral positioning vs supine immobilization

Morbiditya ‐ not reported · critically ill adult patients

1 finding from 1 review

Lateral positioning for critically ill adult patients 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 85 participants
GRADE not reported

Mortality: prone position vs supine

Short‐term mortality (STM)Alive or dead · adults with acute respiratory failure

Mortality: prone position showed no clear difference in short‐term mortality (STM)Alive or dead compared with supine (low certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.84 [0.69, 1.02]
8 studies · 2117 participants
Low

Mortality: prone position vs supine

Longer‐term mortality (LTM)Alive or dead · adults with acute respiratory failure

Mortality: prone position showed no clear difference in longer‐term mortality (LTM)Alive or dead compared with supine (low certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.86 [0.72, 1.03]
8 studies · 2141 participants
Low

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: severe hypoxaemiaAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: severe hypoxaemiaAlive… compared with supine (moderate certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.77 [0.65, 0.92]
7 studies · 977 participants
Moderate

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: lower tidal volume ventilationAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: lower tidal volume… compared with supine (moderate certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.73 [0.55, 0.96]
5 studies · 911 participants
Moderate

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: ARDS onlyAlive or dead · adults with acute respiratory failure

Mortality: prone position showed no clear difference in subgroup analysis of longer‐term mortality: ARDS onlyAlive or dead compared with supine (moderate certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.85 [0.71, 1.01]
8 studies · 1758 participants
Moderate

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: ≥ 16 hours/d proneAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: ≥ 16 hours/d proneAlive… compared with supine (moderate certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.77 [0.61, 0.99]
5 studies · 1005 participants
Moderate

Mortality: prone position vs supine

Subgroup analysis of longer‐term mortality: enrolment ≤ 48 hours after entry criteria/ventilationAlive or dead · adults with acute respiratory failure

Mortality: prone position probably leads to lower subgroup analysis of longer‐term mortality: enrolment ≤ 48 hours… compared with supine (moderate certainty).

1 finding from 1 review

Prone position for acute respiratory failure in adults 2015 · Cochrane Headline outcomes only
RR 0.75 [0.59, 0.94]
5 studies · 1024 participants
Moderate

Semi‐recumbent positioning: 45° vs 25° to 30°

ICU mortality · adults requiring mechanical ventilation

It is very uncertain whether semi‐recumbent positioning: 45° changes ICU mortality compared with 25° to 30° (very low certainty).

1 finding from 1 review

Semi‐recumbent position versus supine position for the prevention of ventilator‐associated pneumonia in adults… 2016 · Cochrane Headline outcomes only
OR 0.57 [0.15, 2.13]
1 study · 30 participants
Very low

Semi‐recumbent positioning: 45° vs 25° to 30°

Hospital mortality · adults requiring mechanical ventilation

It is very uncertain whether semi‐recumbent positioning: 45° changes hospital mortality compared with 25° to 30° (very low certainty).

1 finding from 1 review

Semi‐recumbent position versus supine position for the prevention of ventilator‐associated pneumonia in adults… 2016 · Cochrane Headline outcomes only
OR 1 [0.38, 2.65]
2 studies · 91 participants
Very low