Cochrane · systematic review · CD009946

Semi‐recumbent position versus supine position for the prevention of ventilator‐associated pneumonia in adults requiring mechanical ventilation

Wang, L, Li, X, Yang, Z, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 7 · 58.3%Low 3 · 25%Moderate 2 · 16.7%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Semi‐recumbent position (30º to 60º) versus supine position (0° to 10°) for the prevention of ventilator‐associated pneumonia in adults requiring mechanical ventilation

Population: adults requiring mechanical ventilation
7 questions
OutcomeEffectEvidenceStatus / GRADE
Clinically suspected VAP
Semi‐recumbent position (30º to 60º) vs supine position (0° to 10°)
RR 0.36 [0.25, 0.5]8 studies · 759 participantsModerate
Downgraded: risk of bias
Microbiologically confirmed VAP
Semi‐recumbent position (30º to 60º) vs supine position (0° to 10°)
RR 0.44 [0.11, 1.77]3 studies · 419 participantsVery low
Downgraded: inconsistency, publication bias
ICU mortality
Semi‐recumbent position (30º to 60º) vs supine position (0° to 10°)
RR 0.87 [0.59, 1.27]2 studies · 307 participantsLow
Downgraded: publication bias
Hospital mortality
Semi‐recumbent position (30º to 60º) vs supine position (0° to 10°)
RR 0.84 [0.59, 1.2]3 studies · 346 participantsLow
Downgraded: publication bias
Length of ICU stay
Semi‐recumbent position (30º to 60º) vs supine position (0° to 10°)
no estimate extracted3 studies · 346 participantsModerate
Length of hospital stay
Semi‐recumbent position (30º to 60º) vs supine position (0° to 10°)
no estimate extracted2 studies · 260 participantsVery low
Downgraded: inconsistency, publication bias
Pressure ulcers
Semi‐recumbent position (30º to 60º) vs supine position (0° to 10°)
RR 0.91 [0.6, 1.38]1 study · 221 participantsLow
Downgraded: publication bias

Semi‐recumbent positioning: 45° versus 25° to 30° for the prevention of ventilator‐associated pneumonia in adults requiring mechanical ventilation

Population: adults requiring mechanical ventilation
5 questions
OutcomeEffectEvidenceStatus / GRADE
Clinically suspected VAP
Semi‐recumbent positioning: 45° vs 25° to 30°
RR 0.74 [0.35, 1.56]2 studies · 91 participantsVery low
Downgraded: risk of bias, imprecision
Microbiologically confirmed VAP
Semi‐recumbent positioning: 45° vs 25° to 30°
RR 0.61 [0.2, 1.84]1 study · 30 participantsVery low
Downgraded: risk of bias
ICU mortality
Semi‐recumbent positioning: 45° vs 25° to 30°
OR 0.57 [0.15, 2.13]1 study · 30 participantsVery low
Downgraded: risk of bias
Hospital mortality
Semi‐recumbent positioning: 45° vs 25° to 30°
OR 1 [0.38, 2.65]2 studies · 91 participantsVery low
Downgraded: risk of bias, imprecision
Length of ICU stay
Semi‐recumbent positioning: 45° vs 25° to 30°
MD 1.61 study · 61 participantsVery low
Downgraded: risk of bias