Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

115 questions · 123 findings · 31 reviews · Schizophrenia

No studies found 15 · 12.2%GRADE not reported 19 · 15.4%Very low 36 · 29.3%Low 23 · 18.7%Moderate 26 · 21.1%High 4 · 3.3%

QUETIAPINE vs RISPERIDONE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · schizophrenia

QUETIAPINE probably leads to lower adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (moderate certainty).

1 finding from 1 review

ZUCLOPENTHIXOL ACETATE vs STANDARD DRUG CARE

Global state: 1. Requiring supplementary medication ‐ antipsychotics · patients with acute schizophrenia and similar serious mental illnesses

ZUCLOPENTHIXOL ACETATE showed no clear difference in global state: 1. Requiring supplementary medication ‐ antipsychotics compared with STANDARD DRUG CARE (low certainty).

1 finding from 1 review

Technology‐mediated psychoeducation + standard care intervention vs usual care

Compliance/satisfaction: medication ‐ not compliant ‐ long‐term · schizophrenia

It is very uncertain whether technology‐mediated psychoeducation + standard care intervention changes compliance/satisfaction: medication ‐ not compliant ‐ long‐term compared with standard care intervention (very low certainty).

1 finding from 1 review

α‐FLUPENTHIXOL vs PLACEBO or β‐FLUPENTHIXOL

Global state: clinically important change in global state needing additional medication ‐ chlorpromazine · patients with schizophrenia

It is very uncertain whether α‐FLUPENTHIXOL changes global state: clinically important change in global state needing… compared with PLACEBO or β‐FLUPENTHIXOL (very low certainty).

1 finding from 1 review

ANY FORM OF PSYCHOEDUCATION vs usual care

Compliance: Poor compliance with medication · patients with schizophrenia

It is very uncertain whether ANY FORM OF PSYCHOEDUCATION changes compliance: Not compliant with medication compared with STANDARD CARE (very low certainty).

1 finding from 1 review

Intervention not reported

Concomitant medication (Anxiolytic ‐ Lorazepam) · people with schizophrenia or like psychosis

The intervention may leads to lower concomitant medication (Anxiolytic ‐ Lorazepam) (low certainty).

1 finding from 1 review

ZOTEPINE vs REMOXIPRIDE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · patients with schizophrenia

ZOTEPINE showed no clear difference in adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with REMOXIPRIDE (low certainty).

1 finding from 1 review

ZOTEPINE vs CLOZAPINE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with CLOZAPINE (very low certainty).

1 finding from 1 review

ZOTEPINE vs RISPERIDONE

Adverse effects: Extrapyramidal effects ‐ use of antiparkinson medication ‐ vs 4mg risperidone · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (very low certainty).

1 finding from 1 review

ZOTEPINE vs RISPERIDONE

Adverse effects: Extrapyramidal effects ‐ use of antiparkinson medication ‐ vs 8mg risperidone · patients with schizophrenia

It is very uncertain whether ZOTEPINE changes adverse effects: Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (very low certainty).

1 finding from 1 review

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY vs medication

Global impression: 1. Not able to be discharged (long term) · patients with schizophrenia and severe mental illness

INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY may leads to higher global impression: 1. Not able to be discharged (long term) compared with MEDICATION (low certainty).

1 finding from 1 review