Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,266 questions · 1,314 findings · 160 reviews · Headline outcomes only

No studies found 309 · 23.5%GRADE not reported 34 · 2.6%Very low 356 · 27.1%Low 393 · 29.9%Moderate 187 · 14.2%High 35 · 2.7%

LOD with and without medical ovulation vs medical ovulation induction alone

Live birth · women with anovulatory PCOS and CC resistance

LOD with and without medical ovulation may leads to lower live birth compared with medical ovulation induction alone (low certainty).

2 findings from 1 review

LOD with and without medical ovulation vs medical ovulation induction alone

Multiple pregnancy · women with anovulatory PCOS and CC resistance

LOD with and without medical ovulation probably leads to lower multiple pregnancy compared with medical ovulation induction alone (moderate certainty).

1 finding from 1 review

LOD with and without medical ovulation vs medical ovulation induction alone

Clincial pregnancy · women with anovulatory PCOS and CC resistance

LOD with and without medical ovulation showed no clear difference in clincial pregnancy compared with medical ovulation induction alone (low certainty).

1 finding from 1 review

LOD with and without medical ovulation vs medical ovulation induction alone

Miscarriage · women with anovulatory PCOS and CC resistance

LOD with and without medical ovulation showed no clear difference in miscarriage compared with medical ovulation induction alone (low certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs medical treatment

Death or stroke · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in 30‐day post‐randomisation death/stroke compared with medical treatment alone (low certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs medical treatment

Fatal/non‐fatal stroke in the territory of the treated vertebral artery stenosis(assessed after 30 days post‐randomisation to completion of · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in fatal/non‐fatal stroke in the territory of the treated vertebral… compared with medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs medical treatment

Stroke (ischaemic or haemorrhagic)Median · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in stroke (ischaemic or haemorrhagic)Median compared with medical treatment alone (moderate certainty).

1 finding from 1 review

Biomedical risk assessment vs Control (waitlist, routine/standard oral health education, or minimal intervention)

Smoking cessation · people who smoke

Biomedical risk assessment showed no clear difference in feedback on smoking exposure Smoking cessation at longest compared with standard care or minimal intervention (moderate certainty).

3 findings from 1 review