Findings

What do systematic reviews say?

94 questions · 96 findings · 27 reviews · Airways

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No studies found 6 · 6.3%GRADE not reported 6 · 6.3%Very low 11 · 11.5%Low 31 · 32.3%Moderate 32 · 33.3%High 10 · 10.4%

Ambulatory oxygen vs air

Dyspnea · people with ILD

1 finding from 1 review

Ambulatory and short‐burst oxygen for interstitial lung disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Rehabilitation interventions vs usual care

Dyspnoea ‐ CRQ dyspnoea Scale 1 to 7. Higher is better and 0.5 units is a clinically important difference · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Pulmonary rehabilitation for chronic obstructive pulmonary disease 2015 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 1283 participants
Moderate

Intervention not reported

Health‐related quality of life (cough‐specific) Leicester Cough Questionnaire Scale from 0 to 133; higher score indicates better HRQoL. Contains 19 questions from 3 domains on a Likert scale · individuals with stable bronchiectasis

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Intervention not reported

Health‐related quality of life (health status) COPD Assessment Tool. Scale from 0 to 5; higher score indicates worse HRQoL Contains 10 questions with 5‐point Likert scale · individuals with stable bronchiectasis

The intervention showed no clear difference in health‐related quality of life (health status) COPD Assessment Tool.… (low certainty).

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Low

Intervention not reported

Quality of life (dyspnoea) Measured on the CRQ, the output is a number from 0 to 7, where higher on the scale is better. MID is 0.5. · adults with COPD who had exertional dyspnoea but did not fulfil the criteria for long‐term oxygen treatment

The intervention probably leads to higher quality of life (dyspnoea) Measured on the CRQ, the output is a… (moderate certainty).

1 finding from 1 review

Ambulatory oxygen for people with chronic obstructive pulmonary disease who are not hypoxaemic at rest 2014 · Cochrane Headline outcomes only
MD 0.28 [0.1, 0.45]
4 studies · 341 participants
Moderate

Intervention not reported

Growth velocity over 12 months (cm/y) (higher is better) · children with persistent asthma

The intervention leads to higher growth velocity over 12 months (cm/y) (higher is better) (high certainty).

1 finding from 1 review

Inhaled corticosteroids in children with persistent asthma: dose‐response effects on growth 2014 · Cochrane Headline outcomes only
MD 0.2 [0.02, 0.39]
4 studies · 728 participants
High

Intervention not reported

Change in height over 3 months (cm) (higher is better) · children with persistent asthma

The intervention showed no clear difference in change in height over 3 months (cm) (higher is better) (moderate certainty).

1 finding from 1 review

Inhaled corticosteroids in children with persistent asthma: dose‐response effects on growth 2014 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 944 participants
Moderate

Intervention not reported

Change in height over 12 months (cm) (higher is better) · children with persistent asthma

The intervention showed no clear difference in change in height over 12 months (cm) (higher is better) (moderate certainty).

1 finding from 1 review

Inhaled corticosteroids in children with persistent asthma: dose‐response effects on growth 2014 · Cochrane Headline outcomes only
MD 0.25
4 studies · 548 participants
Moderate

Intervention not reported

Change in weight over 12 months (kg) (higher is better) · children with persistent asthma

The intervention showed no clear difference in change in weight over 12 months (kg) (higher is better) (low certainty).

1 finding from 1 review

Inhaled corticosteroids in children with persistent asthma: dose‐response effects on growth 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 408 participants
Low

Intervention not reported

Change in BMI over 12 months (kg/m2) (higher is better) · children with persistent asthma

The intervention showed no clear difference in change in BMI over 12 months (kg/m2) (higher is better) (low certainty).

1 finding from 1 review

Inhaled corticosteroids in children with persistent asthma: dose‐response effects on growth 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 408 participants
Low

Intervention not reported

Change in skeletal maturation over 12 months (years) (higher is better) · children with persistent asthma

The intervention may leads to higher change in skeletal maturation over 12 months (years) (higher is… (low certainty).

1 finding from 1 review

Inhaled corticosteroids in children with persistent asthma: dose‐response effects on growth 2014 · Cochrane Headline outcomes only
MD 0.18 [0.02, 0.34]
1 study · 181 participants
Low

Intervention not reported

SGRQ Scores range from 0 to 100, with higher scores indicating more limitations · 18 to 80 years of age with bronchiectasis

The intervention showed no clear difference in SGRQ Scores range from 0 to 100, with higher scores indicating more… (low certainty).

1 finding from 1 review

Combination inhaled corticosteroids and long‐acting beta₂‐agonists for children and adults with bronchiectasis 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Ventilation feedback training plus exercise vs exercise

Health‐related quality of life (Change in CRQ Dyspnoea) CRQ · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 73 participants
Moderate

Titrated oxygen therapy vs high‐flow oxygen therapy

Mortality (respiratory‐ related and all‐cause · adults with acute exacerbations of chronic obstructive pulmonary disease

Titrated oxygen therapy may leads to lower mortality (respiratory‐ related and all‐cause compared with high‐flow oxygen therapy (low certainty).

1 finding from 1 review

Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
RR 0.22 [0.05, 0.97]
1 study · 214 participants
Low

Titrated oxygen therapy vs high‐flow oxygen therapy

Arterial blood gas (pH) · adults with acute exacerbations of chronic obstructive pulmonary disease

1 finding from 1 review

Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 214 participants
Low

Titrated oxygen therapy vs high‐flow oxygen therapy

Ventilation of any type · adults with acute exacerbations of chronic obstructive pulmonary disease

Titrated oxygen therapy showed no clear difference in ventilation of any type compared with high‐flow oxygen therapy (low certainty).

1 finding from 1 review

Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
RR 0.67 [0.29, 1.55]
1 study · 189 participants
Low

Titrated oxygen therapy vs high‐flow oxygen therapy

Length of hospital stay · adults with acute exacerbations of chronic obstructive pulmonary disease

1 finding from 1 review

Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 214 participants
Low

Titrated oxygen therapy vs high‐flow oxygen therapy

Quality of life ‐ not measured · adults with acute exacerbations of chronic obstructive pulmonary disease

The review found no eligible studies for this question.

1 finding from 1 review

Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Titrated oxygen therapy vs high‐flow oxygen therapy

Lung function ‐ not measured · adults with acute exacerbations of chronic obstructive pulmonary disease

The review found no eligible studies for this question.

1 finding from 1 review

Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Titrated oxygen therapy vs high‐flow oxygen therapy

Dyspnoea score ‐ not measured · adults with acute exacerbations of chronic obstructive pulmonary disease

The review found no eligible studies for this question.

1 finding from 1 review

Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found