Length of hospital stay · adults (aged > 16 years) without acute lung injury needing mechanical positive pressure ventilation during their surgery and undergoing…
1 finding from 1 review
Barotrauma (pneumothorax) · adults (aged > 16 years) without acute lung injury needing mechanical positive pressure ventilation during their surgery and undergoing…
It is very uncertain whether low tidal volume changes barotrauma: pneumothorax compared with high tidal volume (very low certainty).
1 finding from 1 review
Intervention not reported
Postoperative delirium (POD) within 7 days (As assessed by any method such as the Mini‐Mental State Examination (MMSE) and Confusion Assessment Method (CAM) in the first week after operation) · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations
The intervention probably leads to lower postoperative delirium (POD) within 7 days (As assessed by any… (moderate certainty).
1 finding from 1 review
Intervention not reported
Postoperative cognitive dysfunction (POCD) (As determined by any method of assessing POCD including a battery of neuropsychological tests according to the criteria described by the International Study of Postoperative Cognitive Dysfunction (ISPOCD)) · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations
The intervention showed no clear difference in postoperative cognitive dysfunction (POCD) (As determined by any… (moderate certainty).
1 finding from 1 review
Intervention not reported
All‐cause mortality · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations
The intervention showed no clear difference in all‐cause mortality (low certainty).
1 finding from 1 review
Intervention not reported
Any postoperative complication · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations
The intervention probably leads to lower any postoperative complication (moderate certainty).
1 finding from 1 review
Intervention not reported
Postoperative length of stay (days) · adults aged 18 years or over undergoing general anaesthesia for non‐cardiac or non‐neurosurgical elective operations
1 finding from 1 review
Postoperative wound or systemic infection · participants undergoing surgery
Dexamethasone showed no clear difference in postoperative wound or systemic infection compared with control (moderate certainty).
1 finding from 1 review
Delayed wound healing · participants undergoing surgery
Dexamethasone showed no clear difference in delayed wound healing compared with control (low certainty).
1 finding from 1 review
Glycaemic response ‐ change from baseline to 2 to 12 hours postoperatively in patients without diabetes · participants undergoing surgery
1 finding from 1 review
Glycaemic response ‐ change from baseline to 10 to 24 hours after surgery in patients with diabetes · participants undergoing surgery
1 finding from 1 review
Postoperative delirium (One study used DRS, three studies used CAM and in one study diagnostic tool was not reported) Time points were up to 4 days postoperatively
It is very uncertain whether summary of findings TIVA changes postoperative delirium (One study used DRS, three studies used CAM… compared with inhalational maintenance of anaesthesia (very low certainty).
1 finding from 1 review
Postoperative cognitive dysfunction (9 studies used MMSE, and 2 of these studies used additional diagnostic tools; 1 study used Trail Making Test and additional diagnostic tools; 3 studies did not report diagnostic tools) Time points were up to 30...
Summary of findings TIVA may leads to lower postoperative cognitive dysfunction (9 studies used MMSE, and 2 of… compared with inhalational maintenance of anaesthesia (low certainty).
1 finding from 1 review
Mortality at 30 days
It is very uncertain whether summary of findings TIVA changes mortality At 30 days compared with inhalational maintenance of anaesthesia (very low certainty).
1 finding from 1 review
Intraoperative hypotension (defined by study authors as change in MAP from baseline)
1 finding from 1 review
Length of stay in PACU
1 finding from 1 review
Length of hospital stay
1 finding from 1 review
Mortality within the longest · adults undergoing non‐cardiac surgery
Continuation showed no clear difference in all‐cause mortality (at longest compared with discontinuation of antiplatelet therapy (low certainty).
1 finding from 1 review
All‐cause mortality (up to 30 days) · adults undergoing non‐cardiac surgery
Continuation showed no clear difference in all‐cause mortality (up to 30 days) compared with discontinuation of antiplatelet therapy (low certainty).
1 finding from 1 review
Blood loss requiring transfusion of blood products (intraoperatively and postoperatively) · adults undergoing non‐cardiac surgery
Continuation showed no clear difference in blood loss requiring transfusion of blood products (intraoperatively… compared with discontinuation of antiplatelet therapy (moderate certainty).
1 finding from 1 review