Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,438 questions · 1,463 findings · 125 reviews · Anaesthesia

No studies found 197 · 13.5%GRADE not reported 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%

Epidural analgesia vs intravenous patient‐controlled analgesia

All‐cause mortality rate at 30 days · adults having abdominal surgery

Epidural analgesia showed no clear difference in all‐cause mortality rate at 30 days compared with intravenous patient‐controlled analgesia (low certainty).

1 finding from 1 review

Epidural analgesia vs intravenous patient‐controlled analgesia

Failure of analgesic technique requiring alternative approach (assessed at any time) · adults having abdominal surgery

Epidural analgesia probably leads to higher failure of analgesic technique requiring alternative approach… compared with intravenous patient‐controlled analgesia (moderate certainty).

1 finding from 1 review

Epidural analgesia vs intravenous patient‐controlled analgesia

Adverse events (assessed at any time during · adults having abdominal surgery

Epidural analgesia showed no clear difference in adverse events (assessed at any time during compared with intravenous patient‐controlled analgesia (low certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

Postoperative complications ‐ Stroke · children and adults undergoing surgery

Active cerebral oxygenation monitoring showed no clear difference in postoperative stroke ( compared with blinded cerebral oxygenation monitoring (low certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

POD: postoperative delirium ( · children and adults undergoing surgery

Active cerebral oxygenation monitoring showed no clear difference in POD: postoperative delirium ( compared with blinded cerebral oxygenation monitoring (low certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

POCD defined by original studies ‐ mild ( · children and adults undergoing surgery

Active cerebral oxygenation monitoring may leads to lower POCD defined by original studies ‐ mild ( compared with blinded cerebral oxygenation monitoring (low certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

POCD: decline in cognitive function ( · children and adults undergoing surgery

Active cerebral oxygenation monitoring showed no clear difference in POCD: decline in cognitive function ( compared with blinded cerebral oxygenation monitoring (moderate certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

Intraoperative mortality or postoperative mortality: Death ( · children and adults undergoing surgery

Active cerebral oxygenation monitoring showed no clear difference in intraoperative mortality or postoperative mortality: Death ( compared with blinded cerebral oxygenation monitoring (low certainty).

1 finding from 1 review

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Mortality within the longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

It is very uncertain whether pulmonary artery perfusion with blood changes all‐cause mortality within longest compared with no perfusion during cardiopulmonary bypass (very low certainty).

1 finding from 1 review

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Number of participants with pulmonary events within longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Participants with ≥ 1SAE within longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

It is very uncertain whether pulmonary artery perfusion with blood changes participants with ≥ 1SAE within longest compared with no perfusion during cardiopulmonary bypass (very low certainty).

1 finding from 1 review

Low tidal volume vs high tidal volume

All‐cause mortality · adults (aged > 16 years) without acute lung injury needing mechanical positive pressure ventilation during their surgery and undergoing…

Low tidal volume showed no clear difference in mortality compared with high tidal volume (low certainty).

1 finding from 1 review

Low tidal volume vs high tidal volume

Pneumonia · adults (aged > 16 years) without acute lung injury needing mechanical positive pressure ventilation during their surgery and undergoing…

Low tidal volume probably leads to lower pneumonia compared with high tidal volume (moderate certainty).

1 finding from 1 review

Low tidal volume vs high tidal volume

Need for postoperative non‐invasive ventilatory support · adults (aged > 16 years) without acute lung injury needing mechanical positive pressure ventilation during their surgery and undergoing…

Low tidal volume probably leads to lower need for postoperative non‐invasive ventilatory support compared with high tidal volume (moderate certainty).

1 finding from 1 review

Low tidal volume vs high tidal volume

Need for postoperative invasive ventilatory support · adults (aged > 16 years) without acute lung injury needing mechanical positive pressure ventilation during their surgery and undergoing…

Low tidal volume probably leads to lower need for postoperative invasive ventilatory support compared with high tidal volume (moderate certainty).

1 finding from 1 review