Use of rescue medication · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
It is very uncertain whether intravenous ketorolac changes number of participants using rescue medication over 4 or 6 hours… compared with placebo (very low certainty).
1 finding from 1 review
Number of participants reporting an adverse event · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants reporting any adverse event compared with placebo (moderate certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants experiencing a serious adverse event compared with placebo (low certainty).
1 finding from 1 review
Participant‐reported pain relief of 50% or greater · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants with at least 50% pain relief over 4 hours compared with another NSAID (low certainty).
1 finding from 1 review
Relief of pain · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
Intravenous ketorolac showed no clear difference in number of participants with at least 50% pain relief over 6 hours compared with another NSAID (moderate certainty).
1 finding from 1 review
Median (mean) time to use of rescue medication · adults (mean study ages 23 to 67 years) with acute postoperative pain after abdominal/pelvic, dental or orthopedic surgeries
1 finding from 1 review
At least 50% reduction in pain · health problem or population
It is very uncertain whether summary of Findings Table ‐ Ibuprofen changes number of participants with at least 50% pain relief at 4 hours compared with placebo (very low certainty).
2 findings from 1 review
Median (mean) time to use of rescue medication · health problem or population
1 finding from 1 review
Number of participants reporting an adverse event · health problem or population
It is very uncertain whether summary of Findings Table ‐ Ibuprofen 300 mg changes number of participants reporting or experiencing any adverse event compared with active comparator (acetaminophen) (very low certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · health problem or population
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Very low
Number of participants using rescue medication over 4 to 6 hours postinterventions · health problem or population
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Median (mean) time to use of rescue medication · health problem or population
1 finding from 1 review
Number of participants reporting an adverse event · health problem or population
Summary of Findings Table ‐ Ibuprofen showed no clear difference in number of participants reporting or experiencing any adverse event compared with placebo (low certainty).
1 finding from 1 review
Number of participants experiencing any serious adverse events · health problem or population
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Very low
At least 50% reduction in pain · health problem or population
It is very uncertain whether summary of Findings Table ‐ Ibuprofen 300 mg changes number of participants with at least 50% pain relief at 4 hours compared with active comparator (acetaminophen) (very low certainty).
2 findings from 1 review
Number of participants using rescue medication over 4 to 6 hours postinterventions · health problem or population
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · women with perineal pain in the early postpartum period
Aspirin may leads to higher adequate pain relief as reported by the woman (4 to 8 hours) compared with placebo (low certainty).
1 finding from 1 review
Need for additional pain relief (4 to 8 hours) · women with perineal pain in the early postpartum period
It is very uncertain whether aspirin changes need for additional pain relief (4 to 8 hours) compared with placebo (very low certainty).
1 finding from 1 review
Maternal adverse events · women with perineal pain in the early postpartum period
It is very uncertain whether aspirin changes maternal adverse effects (4 to 8 hours) compared with placebo (very low certainty).
1 finding from 1 review
Neonatal drug adverse effects · women with perineal pain in the early postpartum period
1 finding from 1 review