Question · asked by 1 review
Ibuprofen vs placebo: At least 50% reduction in pain
- Population
- health problem or population
- Intervention
- Ibuprofen
- Comparison
- placebo
- Outcome
- At least 50% reduction in pain
It is very uncertain whether summary of Findings Table ‐ Ibuprofen changes number of participants with at least 50% pain relief at 4 hours compared with placebo (very low certainty).
What each review found
Include earlier review versionsNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of Findings Table ‐ Ibuprofen vs Placebo Number of participants with at least 50% pain relief at 4 hours · health problem or population It is very uncertain whether summary of Findings Table ‐ Ibuprofen changes number of participants with at least 50% pain relief at 4 hours compared with placebo (very low certainty). Single‐dose intravenous ibuprofen for acute postoperative pain in adults (2021) · Cochrane Headline outcomes only | RR 1.44 [0.77, 2.66] | 1 study · 126 participants | Very low |
Summary of Findings Table ‐ Ibuprofen vs Placebo Number of participants with at least 50% pain relief at 6 hours · health problem or population It is very uncertain whether summary of Findings Table ‐ Ibuprofen changes number of participants with at least 50% pain relief at 6 hours compared with placebo (very low certainty). Single‐dose intravenous ibuprofen for acute postoperative pain in adults (2021) · Cochrane Headline outcomes only | RR 1.44 [0.77, 2.66] | 1 study · 126 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Single‐dose intravenous ibuprofen for acute postoperative pain in adults 2021 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.