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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,956 questions in 143 reviews · Musculoskeletal
current versionsNo studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Change in radiographic progression ‐ not measured · patients with treating rheumatoid arthritis Herbal therapy for treating rheumatoid arthritis (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Achievement of low disease state (DAS 28) ‐ not measured · patients with treating rheumatoid arthritis Herbal therapy for treating rheumatoid arthritis (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR ACR 50% improvement ( · patients with Rheumatoid arthritis Herbal therapy for treating rheumatoid arthritis (2011) · Cochrane | RR 11.92 [0.73, 193.38] | 1 study · 23 participants | Low |
Intervention NR Change in pain ‐ not measured · patients with Rheumatoid arthritis Herbal therapy for treating rheumatoid arthritis (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR HAQ disability score ‐ not measured · patients with Rheumatoid arthritis Herbal therapy for treating rheumatoid arthritis (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Patient reported global impression of clinical change (PGIC) 'good' or 'very good' PGIC scale: Very poor, Poor, No change, Good, Very good. · patients with rheumatoid arthritis pain Opioid therapy for treating rheumatoid arthritis pain (2011) · Cochrane | RR 1.44 [1.03, 2.03] | 3 studies · 324 participants | Low |
Intervention NR Withdrawal due to inadequate analgesia · patients with rheumatoid arthritis pain Opioid therapy for treating rheumatoid arthritis pain (2011) · Cochrane | RR 0.82 [0.34, 2.01] | 4 studies · 345 participants | Low |
Intervention NR Functional status (HAQ) HAQ. Scale from: 0 to 3. · patients with rheumatoid arthritis pain Opioid therapy for treating rheumatoid arthritis pain (2011) · Cochrane | no estimate extracted | 2 studies · 243 participants | Low |
Intervention NR Withdrawal due to adverse events · patients with rheumatoid arthritis pain Opioid therapy for treating rheumatoid arthritis pain (2011) · Cochrane | RR 2.67 [0.52, 13.75] | 3 studies · 331 participants | Low |
Intervention NR Participants reporting adverse events · patients with rheumatoid arthritis pain Opioid therapy for treating rheumatoid arthritis pain (2011) · Cochrane | OR 3.9 [2.31, 6.56] | 4 studies · 371 participants | Low |
Intervention NR Serious adverse events · patients with rheumatoid arthritis pain Opioid therapy for treating rheumatoid arthritis pain (2011) · Cochrane | no estimate extracted | 2 studies · 317 participants | Low |
Intervention NR Pain ‐ not measured · patients with chronic (>12 months) lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Adverse events ‐ not measured · patients with chronic (mean 23 months) lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Pain ‐ not reported · patients with chronic (>6 months) lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Disabilty ‐ not measured · patients with chronic (>6 months) lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Adverse events ‐ not measured · patients with chronic (>6 months) lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Disability DASH scale. Scale from: 0 to 100. ( · patients with chronic (>12 months) lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | 1 study · 47 participants | Low |
Intervention NR Adverse events ‐ not measured · patients with chronic (>12 months) lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Pain‐ short term VAS scale. Scale from: 0 to 10. ( · patients with lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | 1 study · 24 participants | Moderate |
Intervention NR Pain‐ long term VAS. Scale from: 0 to 10. ( · patients with lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | 1 study · 24 participants | Low |
Intervention NR Disability Mayo Elbow Performance. Scale from: 0 to 100. ( · patients with lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | 1 study · 24 participants | Low |
Intervention NR Adverse events ‐ not reported · patients with lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Pain ‐ not reported · patients with chronic (mean 23 months) lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Disability ‐ not measured · patients with chronic (mean 23 months) lateral elbow pain Surgery for lateral elbow pain (2011) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Pulmonary Methotrexate pneumonitis · patients with inflammatory arthritis on methotrexate Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people… (2011) · Cochrane | no estimate extracted | 2 studies · 27 participants | Moderate |
Intervention NR Hepatic Liver histology/hepatic enzyme abnormalities2 · patients with inflammatory arthritis on methotrexate Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people… (2011) · Cochrane | no estimate extracted | 2 studies · 272 participants | Low |
Intervention NR Renal Glomerular and tubular injury · patients with inflammatory arthritis on methotrexate Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people… (2011) · Cochrane | no estimate extracted | 2 studies · 30 participants | Low |
Intervention NR Haematological Thrombocytopenia · patients with inflammatory arthritis on methotrexate Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people… (2011) · Cochrane | no estimate extracted | 0 studies · 1 participants | Moderate |
Intervention NR Withdrawal due to adverse events Methotrexate discontinuation · patients with inflammatory arthritis on methotrexate Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people… (2011) · Cochrane | no estimate extracted | 3 studies · 632 participants | Low |
Intervention NR All adverse events · patients with inflammatory arthritis on methotrexate Safety of non‐steroidal anti‐inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people… (2011) · Cochrane | no estimate extracted | 7 studies · 283 participants | Moderate |
Tricyclic antidepressant vs control Pain < 1 week VAS scale 0 to 100 mm · patients with pain management in RA Antidepressants for pain management in rheumatoid arthritis (2011) · Cochrane | no estimate extracted | 1 study · 30 participants | Very low |
Tricyclic antidepressant vs control Pain 1 to 6 weeks Any pain measurement scale · patients with pain management in RA Antidepressants for pain management in rheumatoid arthritis (2011) · Cochrane | no estimate extracted | 7 studies · 482 participants | Very low |
Tricyclic antidepressant vs control Pain > 6 weeks Any pain measurement scale · patients with pain management in RA Antidepressants for pain management in rheumatoid arthritis (2011) · Cochrane | no estimate extracted | 5 studies · 368 participants | Very low |
Tricyclic antidepressant vs control Functional Status Health Assessment Questionnaire (HAQ) scale 0 to 3 · patients with pain management in RA Antidepressants for pain management in rheumatoid arthritis (2011) · Cochrane | no estimate extracted | 1 study · 28 participants | Low |
Tricyclic antidepressant vs control Number of Withdrawals due to Adverse Events patient interview · patients with pain management in RA Antidepressants for pain management in rheumatoid arthritis (2011) · Cochrane | RR 0.98 [0.59, 1.64] | 6 studies · 455 participants | Very low |
Tricyclic antidepressant vs control Total number of adverse events patient interview · patients with pain management in RA Antidepressants for pain management in rheumatoid arthritis (2011) · Cochrane | RR 1.83 [1.01, 3.3] | 6 studies · 455 participants | Very low |
Intervention NR Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with peripheral joint osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | 9 studies · 1835 participants | Low |
Intervention NR Function (long term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with knee osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | 4 studies · 1398 participants | High |
Intervention NR Adverse events · Patients with knee osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Side effects of acupuncture‐Bruising and bleeding at injection site · Patients with knee osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Function (short term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with peripheral joint osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | 8 studies · 1767 participants | Low |
Intervention NR Pain (long term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with peripheral joint osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | 4 studies · 1399 participants | High |
Intervention NR Function (long term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with peripheral joint osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | 4 studies · 1398 participants | High |
Intervention NR Adverse events · Patients with peripheral joint osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Side effects of acupuncture‐Bruising and bleeding at injection site · Patients with peripheral joint osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with knee osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | 8 studies · 1773 participants | Low |
Intervention NR Function (short term) WOMAC scale from 0 to 68 points (higher is worse function). · Patients with knee osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | 8 studies · 1767 participants | Low |
Intervention NR Pain (long term) WOMAC scale from 0 to 20 points (higher is worse pain). · Patients with knee osteoarthritis Acupuncture for peripheral joint osteoarthritis (2010) · Cochrane | no estimate extracted | 4 studies · 1399 participants | High |
Intervention NR Pain VAS pain scales · Patients with knee osteoarthritis (none of the trials included patients with hip osteoarthritis) Therapeutic ultrasound for osteoarthritis of the knee or hip (2010) · Cochrane | no estimate extracted | 5 studies · 320 participants | Low |
Intervention NR Function Various validated function scales · Patients with knee osteoarthritis (none of the trials included patients with hip osteoarthritis) Therapeutic ultrasound for osteoarthritis of the knee or hip (2010) · Cochrane | no estimate extracted | 4 studies · 251 participants | Low |